Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035166 | 1.00 | ACHE (0.45) | ACHEKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL14268895 | 0.85 | ACHE (0.47) | ACHEKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL4840315 | 0.82 | ACHE (0.49) | ACHEKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL4836544 | 0.80 | KDM4E (0.46) | ACHEKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL5434394 | 0.80 | PIM1 (0.42) | ACHEKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL5554556 | 0.80 | PIM1 (0.42) | ACHEKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL4837847 | 0.80 | KDM4E (0.43) | ACHEKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL4839424 | 0.80 | MAPK8 (0.46) | ACHEKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL4835587 | 0.80 | SIRT5 (0.48) | ACHEKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL4838822 | 0.80 | ACHE (0.45) | ACHEKDM4EALDH1A1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335656-B2 | Stent with a disposed traiazine compound such as 6-(3-Chloro-4-methoxy-phenoxy)-N-cycloheptyl-N'-methyl-N'-(1-methyl-piperidin-4-yl)-[1,3,5]triazine-2,4-diamine for inhibiting smooth muscle proliferation; restenosis and atherosclerosis | REDDY US THERAPEUTICS, INC. (US) | 2008-02-26 | — | — | US | disclosed |