SCHEMBL5032509

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5032552	0.92	NPC1 (0.45)	HPGDALDH1A1HSD17B10CYP3A4TRPC3
	SCHEMBL5035137	0.92	CYP3A4 (0.43)	HPGDALDH1A1HSD17B10CYP3A4TRPC3
	SCHEMBL5032533	0.90	HTR2C (0.42)	HPGDALDH1A1HSD17B10TRPC3TRPC6
	SCHEMBL5032685	0.89	GABRA2 (0.46)	HPGDALDH1A1HSD17B10CYP3A4TRPC3
	SCHEMBL5032522	0.89	HTR2C (0.48)	HPGDNPC1RAB9AKMT2AMEN1
	SCHEMBL5035187	0.89	NPC1 (0.41)	HPGDALDH1A1TRPC3TRPC6NPC1
	SCHEMBL5032645	0.88	CYP3A4 (0.40)	HPGDCYP3A4TRPC3TRPC6NPC1
	SCHEMBL5034840	0.88	CYP3A4 (0.37)	HPGDCYP3A4TRPC3TRPC6NPC1
	SCHEMBL5034878	0.86	KMT2A (0.48)	ALDH1A1RAB9AKMT2AMEN1PTGS2
	SCHEMBL5032538	0.85	HTR2C (0.42)	HPGDCYP3A4TRPC3TRPC6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.