SCHEMBL5032541

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5034751	0.92	CYP3A4 (0.47)	CYP3A4ALDH1A1GABRA2GABRB2L3MBTL1
	SCHEMBL5035304	0.92	CYP3A4 (0.54)	CYP3A4ALDH1A1GABRA2GABRB2L3MBTL1
	SCHEMBL5038953	0.90	CYP3A4 (0.46)	CYP3A4NPC1RAB9ASMN1; SMN2MEN1
	SCHEMBL14190164	0.90	CYP3A4 (0.45)	CYP3A4ALDH1A1GABRA2GABRB2MAPT
	SCHEMBL5034815	0.90	KDM4E (0.43)	CYP3A4ALDH1A1MAPTNPC1RAB9A
	SCHEMBL5035888	0.89	CYP3A4 (0.45)	CYP3A4NPC1SMN1; SMN2MEN1CYP1A2
	SCHEMBL5034860	0.89	CYP3A4 (0.47)	CYP3A4ALDH1A1MAPTNPC1RAB9A
	SCHEMBL5041129	0.89	CYP3A4 (0.41)	CYP3A4NPC1MEN1KMT2A
	SCHEMBL5486463	0.89	CYP3A4 (0.49)	CYP3A4ALDH1A1GABRA2GABRB2L3MBTL1
	SCHEMBL5039048	0.89	CYP3A4 (0.43)	CYP3A4ALDH1A1L3MBTL1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.