SCHEMBL5041129

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5035942	0.90	RAB9A (0.41)	DHODHSCN10AHCRTR2MEN1NPC1
	SCHEMBL5032541	0.89	CYP3A4 (0.52)	CYP3A4MEN1NPC1KMT2A
	SCHEMBL5035123	0.87	DHODH (0.42)	CYP3A4GCGRGIPRTRPV1TRPM8
	SCHEMBL5039048	0.82	CYP3A4 (0.43)	CYP3A4HCRTR2MEN1NPC1KMT2A
	SCHEMBL5034876	0.82	CYP3A4 (0.43)	CYP3A4HCRTR2MEN1NPC1KMT2A
	SCHEMBL5035020	0.82	NPC1 (0.39)	GCGRGIPRTRPV1DHODHMEN1
	SCHEMBL5034751	0.82	CYP3A4 (0.47)	CYP3A4MEN1NPC1KMT2ANPSR1
	SCHEMBL5035304	0.81	CYP3A4 (0.54)	CYP3A4MEN1NPC1KMT2A
	SCHEMBL5038953	0.80	CYP3A4 (0.46)	CYP3A4MEN1NPC1KMT2A
	SCHEMBL14190164	0.80	CYP3A4 (0.45)	CYP3A4MEN1NPC1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.