Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028055 | 0.86 | LMNA (0.45) | TSHRGAAHTTCA1CA2 | |
| SCHEMBL11160381 | 0.78 | POLB (0.51) | TSHRGAAHTTTP53POLB | |
| SCHEMBL6342266 | 0.78 | GAA (0.51) | TSHRGAAHTTTP53POLB | |
| SCHEMBL1576395 | 0.78 | TSHR (0.44) | TSHRGAAHTTTP53POLB | |
| SCHEMBL138352 | 0.78 | HSD17B10 (0.44) | TSHRGAAHTTTP53POLB | |
| SCHEMBL28812800 | 0.78 | CA1 (0.40) | POLBCA1CA2CA9LMNA | |
| SCHEMBL2492882 | 0.74 | CYP1A2 (0.62) | TSHRGAAHTTTP53POLB | |
| SCHEMBL2489467 | 0.74 | TSHR (0.47) | TSHRGAAHTTTP53POLB | |
| SCHEMBL14808678 | 0.74 | HTT (0.47) | TSHRGAAHTTTP53POLB | |
| SCHEMBL6342292 | 0.72 | GAA (0.44) | TSHRGAAHTTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399841-B1 | High-energy 1,3,5-triazinyl diazenes, and process thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2008-07-15 | — | — | US | disclosed |
| US-7399841-B1 | High-energy 1,3,5-triazinyl diazenes, and process thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2008-07-15 | — | — | US | disclosed |
| US-7399841-B1 | High-energy 1,3,5-triazinyl diazenes, and process thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2008-07-15 | — | — | US | disclosed |