SCHEMBL138352

SCHEMBL138352

COc1nc(N)nc(N)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.44
TSHR P16473 2/20 0.44
HTT P42858 2/20 0.44
TP53 P04637 1/20 0.44
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
CCNA2 P20248 1/20 0.37
CDK2 P24941 1/20 0.37
CCNA1 P78396 1/20 0.37
NPC1 O15118 3/20 0.36
LMNA P02545 1/20 0.36
PIK3CA P42336 1/20 0.35
ATM Q13315 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MAPT P10636 1/20 0.34
RECQL P46063 1/20 0.34
ALDH1A1 P00352 3/20 0.33
CYP2D6 P10635 1/20 0.33
DYRK1A Q13627 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1576395 0.94 TSHR (0.44) HSD17B10TSHRHTTTP53POLB
SCHEMBL30562916 0.84 HSP90AB1 (0.43) HSD17B10TSHRHTTTP53POLB
SCHEMBL441545 0.84 HSP90AB1 (0.43) HSD17B10TSHRHTTTP53POLB
SCHEMBL7250707 0.82 TP53 (0.39) HSD17B10TSHRHTTTP53POLB
SCHEMBL1577050 0.82 HSP90AA1 (0.50) HSD17B10TSHRHTTTP53POLB
SCHEMBL9266759 0.82 TP53 (0.39) HSD17B10TSHRHTTTP53POLB
Fluoride SCHEMBL31379739 0.82 HSP90AB1 (0.41) HSD17B10TSHRHTTTP53POLB
Pyrophosphoric Acid SCHEMBL15367332 0.80 TDP1 (0.40) HSD17B10TSHRHTTTP53POLB
SCHEMBL1710312 0.80 HSP90AB1 (0.56) HSD17B10TSHRHTTTP53POLB
Methoxymethane SCHEMBL108410 0.79 LMNA (0.43) HSD17B10POLBGAACCNA2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025013869-A1 FLUORINE-CONTAINING POLYMER HAVING NITROGEN-CONTAINING AROMATIC RING, PRODUCTION METHOD THEREFOR, AND COMPOSITION THEREOF ダイキン工業株式会社 2025-01-16 WO claimed
CN-106458847-B Novel diamine synthesis and liquid crystal aligning agent using the same 东进世美肯株式会社 2020-04-24 CN claimed
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INST SCI & TECH (KR) 2018-03-08 US claimed
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-07-07 US claimed
EP-2940015-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT Korea Advanced Institute of Science and Technology (KR) 2015-11-04 EP claimed
CN-101812304-B Liquid crystal aligning agent, liquid crystal display device and fabricating method thereof JSR CO LTD 2014-03-19 CN claimed
CN-101024773-B Liquid crystal aligning agent and liquid crystal display device JSR CORP 2013-01-23 CN claimed
US-6562844-B2 Attaching an olefin to a solid support; oxidizing the olefin to provide an epoxide functionality; opening the epoxide with an amine to form an amino alcohol; cyclizing the amino alcohol using a phosgene equivalent PHARMACIA & UPJOHN COMPANY 2003-05-13 US claimed
EP-0397582-B1 Imide groups containing polymers made from hindered diamines CIBA GEIGY AG (CH) 1994-12-14 EP claimed
US-5122590-A Addition-condensation copolymer comprising an N,N*-bismaleimide, hindered aromatic diprimary diamine, a diamino-s-triazine, a halogenated epoxy resin and a diallyl oxylated benzene; heat resistance; prepregs RHONE-POULENC CHIMIE (FR) 1992-06-16 US claimed
US-4797340-A Dry electrophotographic toner comprising graft copolymer FUJI XEROX CO., LTD. (JP) 1989-01-10 US claimed
EP-4715001-A1 HORIZONTAL MEMBER FOR AUTOMOBILES AND METHOD FOR MANUFACTURING SAME TEIJIN LIMITED (JP) 2026-03-25 EP disclosed
EP-4083168-B1 FLAME RETARDANT COMPOSITION AND FLAME-RETARDANT THERMOPLASTIC RESIN COMPOSITION CONTAINING SAID FLAME RETARDANT COMPOSITION DAIHACHI CHEM IND (JP) 2026-02-18 EP disclosed
EP-3708636-B1 FLAME RETARDANT COMPOSITION AND FLAME-RETARDANT THERMOPLASTIC RESIN COMPOSITION CONTAINING SAID FLAME RETARDANT COMPOSITION DAIHACHI CHEM IND (JP) 2026-02-11 EP disclosed
US-20250388743-A1 PROPYLENE-BASED RESIN COMPOSITION AND MOLDED ARTICLE SUMITOMO CHEMICAL CO (JP) 2025-12-25 US disclosed
EP-0078784-B1 THIO-SUBSTITUTED-1,3,5-TRIAZINE-DIAMINES AND -TRIAMINES USEFUL AS PREVULCANIZATION INHIBITORS MONSANTO COMPANY (US) 1985-07-03 EP disclosed
US-4506053-A BNLEND WITH POLYCYANURATES, AMINE SUBSTITUTED TRIAZINE AND/OR CYANOGUANIDINE, AND FILLER MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1985-03-19 US disclosed
US-4460769-A Thio-amino-1,3,5-triazines MONSANTO COMPANY (US) 1984-07-17 US disclosed
EP-0078784-A1 Thio-substituted-1,3,5-triazine-diamines and -triamines useful as prevulcanization inhibitors MONSANTO COMPANY (US) 1983-05-11 EP disclosed
US-4380609-A Prevulcanization inhibitors of thio-triazine-amines for rubber MONSANTO COMPANY (US) 1983-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388743-A1 PROPYLENE-BASED RESIN COMPOSITION AND MOLDED ARTICLE TAF1, PFN1, PAF1 HSD17B10 1531/4885TSHR 2794/4885HTT 3308/4885
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT RICTOR, SGTA, SLC43A1 HSD17B10 1867/4885TSHR 4415/4885HTT 1820/4885
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT SGTA, RICTOR, SLC43A1 HSD17B10 1974/4885TSHR 4346/4885HTT 1663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.