SCHEMBL5032585

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5032525	0.91	CRHR1 (0.39)	CYP3A4CRHR1KMT2AMEN1HTT
	SCHEMBL5035304	0.87	CYP3A4 (0.54)	CYP3A4CRHR1CYP1A2CYP2D6CYP2C9
	SCHEMBL5034783	0.85	CYP3A4 (0.43)	CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL5035876	0.85	CYP3A4 (0.50)	CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL5034786	0.85	CYP3A4 (0.44)	CYP3A4KMT2AALDH1A1KDM4E
	SCHEMBL5034860	0.84	CYP3A4 (0.47)	CYP3A4KMT2AMEN1HTTSMN1; SMN2
	SCHEMBL5486463	0.84	CYP3A4 (0.49)	CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL14190174	0.83	CYP3A4 (0.48)	CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL5034751	0.83	CYP3A4 (0.47)	CYP3A4CRHR1CYP1A2CYP2D6CYP2C9
	SCHEMBL14190164	0.83	CYP3A4 (0.45)	CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.