Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034466 | 0.91 | HTT (0.43) | PPARAPPARGPPARDMAPTTHRB | |
| SCHEMBL5032820 | 0.88 | PPARA (0.40) | PPARAPPARGPPARDHPGDALDH1A1 | |
| SCHEMBL5032738 | 0.88 | PPARA (0.40) | PPARAPPARGPPARDMAPTTHRB | |
| SCHEMBL5031908 | 0.87 | PPARA (0.41) | PPARAPPARGPPARDMAPTHPGD | |
| SCHEMBL5031737 | 0.87 | PPARA (0.41) | PPARAPPARGPPARD | |
| SCHEMBL5032956 | 0.86 | HRH3 (0.38) | PDE4APDE4BPDE4CPDE4DEPHX2 | |
| SCHEMBL5029970 | 0.84 | PPARA (0.44) | PPARAPPARGPPARDMAPTHPGD | |
| SCHEMBL5031836 | 0.84 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DEPHX2 | |
| SCHEMBL5031904 | 0.82 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DEPHX2 | |
| SCHEMBL5032817 | 0.82 | PPARD (0.47) | PPARAPPARGPPARDMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |