Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.40 |
| ▸ | PPARD | Q03181 | 10/20 | 0.40 |
| ▸ | PPARG | P37231 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034466 | 0.94 | HTT (0.43) | PPARAPPARDPPARGMAPTTHRB | |
| SCHEMBL5032820 | 0.91 | PPARA (0.40) | PPARAPPARDPPARGHPGDALDH1A1 | |
| SCHEMBL5031908 | 0.89 | PPARA (0.41) | PPARAPPARDPPARGMAPTHPGD | |
| SCHEMBL5031737 | 0.89 | PPARA (0.41) | PPARAPPARDPPARG | |
| SCHEMBL5032979 | 0.88 | PDE4A (0.42) | PPARAPPARDPPARGMAPTTHRB | |
| SCHEMBL5029970 | 0.86 | PPARA (0.44) | PPARAPPARDPPARGMAPTHPGD | |
| SCHEMBL5029832 | 0.86 | ALDH1A1 (0.39) | PPARAPPARDPPARGMAPTHPGD | |
| SCHEMBL5032817 | 0.84 | PPARD (0.47) | PPARAPPARDPPARGMAPTHPGD | |
| SCHEMBL5029881 | 0.82 | PPARA (0.40) | PPARAPPARDPPARGMAPTTHRB | |
| SCHEMBL5034465 | 0.82 | PPARA (0.48) | PPARAPPARDPPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |