Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034466 | 0.92 | HTT (0.43) | PPARAPPARDPPARGMAPTKMT2A | |
| SCHEMBL5029970 | 0.90 | PPARA (0.44) | PPARAPPARDPPARGMAPTKMT2A | |
| SCHEMBL5032820 | 0.89 | PPARA (0.40) | PPARAPPARDPPARGHPGD | |
| SCHEMBL5032738 | 0.89 | PPARA (0.40) | PPARAPPARDPPARGMAPTLMNA | |
| SCHEMBL5031737 | 0.88 | PPARA (0.41) | PPARAPPARDPPARG | |
| SCHEMBL5032979 | 0.87 | PDE4A (0.42) | PPARAPPARDPPARGMAPTLMNA | |
| SCHEMBL5032900 | 0.86 | ANO1 (0.49) | MEN1KMT2ALMNAHPGDADRB2 | |
| SCHEMBL5031740 | 0.85 | PPARA (0.44) | PPARAPPARDPPARGTSHRRECQL | |
| SCHEMBL5032817 | 0.84 | PPARD (0.47) | PPARAPPARDPPARGMAPTHPGD | |
| SCHEMBL5031870 | 0.83 | LMNA (0.43) | RECQLMEN1KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |