Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29175226 | 0.86 | SMN1; SMN2 (0.36) | SMN1; SMN2DGAT1MAPTHTTKDM4E | |
| SCHEMBL29175217 | 0.81 | DGAT1 (0.38) | SMN1; SMN2DGAT1HTTLMNACES2 | |
| SCHEMBL27539515 | 0.80 | GRIN2D (0.38) | SMN1; SMN2MAPTHTTKDM4ELMNA | |
| SCHEMBL29175211 | 0.80 | NNMT (0.33) | SMN1; SMN2DGAT1PARP1CDC7MAP2K2 | |
| SCHEMBL27856987 | 0.79 | DGAT1 (0.39) | SMN1; SMN2DGAT1HTTLMNACES2 | |
| SCHEMBL6186161 | 0.79 | PARP1 (0.41) | SMN1; SMN2DGAT1MAPTHTTKDM4E | |
| SCHEMBL27539502 | 0.79 | GRIN2D (0.37) | SMN1; SMN2MAPTHTTKDM4ELMNA | |
| SCHEMBL29175216 | 0.78 | SMN1; SMN2 (0.34) | SMN1; SMN2DGAT1MAPTHTTKDM4E | |
| SCHEMBL11461751 | 0.78 | DGAT1 (0.38) | DGAT1PARP1CDC7MAP2K2MAP2K1 | |
| Hydrochloric Acid SCHEMBL28556037 | 0.76 | DGAT1 (0.37) | DGAT1PARP1CDC7MAP2K2MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143941-B | Synthesis method of intermediate of balusavir mefene | 北京四环制药有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-110143941-A | A kind of synthetic method of Barrow Sa Weimabo ester intermediate | 北京四环制药有限公司 | 2019-08-20 | — | — | CN | disclosed |
| EP-2001866-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007117982-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2007-10-18 | — | — | WO | disclosed |