Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DDX3X | O00571 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330495 | 0.96 | PBRM1 (0.61) | PBRM1ALDH1A1NPC1MITFLMNA | |
| SCHEMBL29841359 | 0.96 | PBRM1 (0.61) | PBRM1ALDH1A1NPC1MITFLMNA | |
| Hydrochloric Acid SCHEMBL27603078 | 0.94 | PBRM1 (0.59) | PBRM1ALDH1A1NPC1MITFLMNA | |
| Hydrochloric Acid SCHEMBL4369239 | 0.94 | PBRM1 (0.59) | PBRM1ALDH1A1NPC1MITFLMNA | |
| Methoxymethane SCHEMBL28316131 | 0.90 | PBRM1 (0.55) | PBRM1ALDH1A1NPC1MITFLMNA | |
| SCHEMBL3786043 | 0.84 | FYN (0.57) | PBRM1ALDH1A1NPC1MITFLMNA | |
| Formic Acid Methyl Ester SCHEMBL28045566 | 0.83 | PBRM1 (0.49) | PBRM1ALDH1A1NPC1MITFLMNA | |
| Ether SCHEMBL10473020 | 0.83 | ALDH1A1 (0.49) | PBRM1ALDH1A1NPC1MITFLMNA | |
| SCHEMBL27801317 | 0.82 | NPC1 (0.57) | PBRM1ALDH1A1NPC1MITFLMNA | |
| Acetophenone SCHEMBL28462740 | 0.81 | MAPT (0.54) | PBRM1ALDH1A1NPC1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214708-A1 | Asymmetrically substituted phosphinic acids | CLARIANT INTERNATIONAL LTD. | 2008-09-04 | — | — | US | disclosed |