SCHEMBL330495

SCHEMBL330495

CC(=O)c1cccc(N)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.61
ALDH1A1 P00352 6/20 0.57
NPC1 O15118 1/20 0.56
MITF O75030 1/20 0.56
LMNA P02545 1/20 0.56
POLB P06746 1/20 0.56
F2 P00734 1/20 0.52
PLG P00747 1/20 0.52
PRSS1 P07477 1/20 0.52
PRSS2 P07478 1/20 0.52
PRSS3 P35030 1/20 0.52
DDX3X O00571 1/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
CYP3A4 P08684 1/20 0.48
CASP1 P29466 1/20 0.48
RECQL P46063 1/20 0.48
FYN P06241 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29841359 1.00 PBRM1 (0.61) PBRM1ALDH1A1NPC1MITFLMNA
Hydrochloric Acid SCHEMBL27603078 0.98 PBRM1 (0.59) PBRM1ALDH1A1NPC1MITFLMNA
Hydrochloric Acid SCHEMBL4369239 0.98 PBRM1 (0.59) PBRM1ALDH1A1NPC1MITFLMNA
Formaldehyde SCHEMBL5033089 0.96 PBRM1 (0.57) PBRM1ALDH1A1NPC1MITFLMNA
Methoxymethane SCHEMBL28316131 0.94 PBRM1 (0.55) PBRM1ALDH1A1NPC1MITFLMNA
SCHEMBL3786043 0.88 FYN (0.57) PBRM1ALDH1A1NPC1MITFLMNA
Formic Acid Methyl Ester SCHEMBL28045566 0.87 PBRM1 (0.49) PBRM1ALDH1A1NPC1MITFLMNA
Ether SCHEMBL10473020 0.87 ALDH1A1 (0.49) PBRM1ALDH1A1NPC1MITFLMNA
SCHEMBL27801317 0.86 NPC1 (0.57) PBRM1ALDH1A1NPC1MITFLMNA
SCHEMBL28418793 0.83 NOS1 (0.53) PBRM1ALDH1A1NPC1MITFLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2159 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528777-B2 Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2026-01-20 US claimed
CN-116410436-B Preparation method and application of carboxyl-terminated hyperbranched polyamide internal crosslinking modified aqueous polyurea 扬州市祥华新材料科技有限公司 2025-06-24 CN claimed
CN-119431040-A Precipitation supported coated slow-release carbon-based iron fertilizer and preparation method thereof 江西省农业科学院土壤肥料与资源环境研究所 2025-02-14 CN claimed
CN-119431041-A Precipitation supported slow-release carbon-based iron fertilizer and preparation method thereof 江西省农业科学院土壤肥料与资源环境研究所 2025-02-14 CN claimed
CN-119431042-A Precipitation supported alkaline coated slow-release carbon-based iron fertilizer, preparation method and precise application method thereof 江西省农业科学院土壤肥料与资源环境研究所 2025-02-14 CN claimed
CN-114591253-B Urea feed additive and preparation method and application thereof 山东博沂饲料科技有限公司 2024-09-24 CN claimed
CN-118451062-A Preparation and use of quinazolinediones 科学与工业研究会(按照印度社会团体注册法案(1860年第21号法案)设立的注册机构) 2024-08-06 CN claimed
CN-116554619-B Fluororubber elastomer and preparation method thereof 上海芯密科技有限公司 2024-03-08 CN claimed
CN-117327244-A Self-sensitization type radiochromic polyurethane elastomer and preparation method thereof 四川大学 2024-01-02 CN claimed
US-20230357165-A1 QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2023-11-09 US claimed
US-5672352-A Methods of identifying the avian repellent effects of a compound and methods of repelling birds from materials susceptible to consumption by birds MONELL CHEMICAL SENSES CENTER (US) 1997-09-30 US claimed
US-5599629-A EPOXY RESIN HAVING AT LEAST ONE GLYCIDYL AMINE GROUP AND THREE OR MORE EPOXIDE GROUPS PER MOLECULE, AROMATIC AMINE HARDENER SUBSTITUTED WITH ELECTRON WITHDRAWING GROUP IN SPECIFIED STOICHIOMETRY AMOCO CORPORATION (US) 1997-02-04 US claimed
EP-0705316-A1 EPOXY ADHESIVE COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-04-10 EP claimed
US-5464625-A Non-toxic methods of repelling rodents from materials susceptible to rodent consumption MONELL CHEMICAL SENSES CENTER (US) 1995-11-07 US claimed
US-5280067-A Heat curable adhesive MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-01-18 US claimed
WO-1994000527-A1 EPOXY ADHESIVE COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-01-06 WO claimed
WO-1992017062-A1 METHOD OF IDENTIFYING THE AVIAN REPELLANT EFFECTS OF A COMPOUND AND METHOD OF REPELLING BIRDS FROM MATERIALS SUSCEPTIBLE TO CONSUMPTION BY BIRDS MONELL CHEMICAL SENSES CENTER (US) 1992-10-15 WO claimed
EP-0105641-B1 PRODUCTION OF M-FLUOROACETOPHENONE OLIN CORPORATION (US) 1986-05-14 EP claimed
US-4487969-A DIAZOTIZATION OF M-AMINOACETOPHENONE FOLLOWED BY HEAT DECOMPOSITION OLIN CORPORATION (US) 1984-12-11 US claimed
EP-0105641-A1 Production of m-fluoroacetophenone OLIN CORPORATION (US) 1984-04-18 EP claimed