Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD209 | Q9NNX6 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | IGF2R | P11717 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | AMY2A | P04746 | 2/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18191573 | 0.81 | CA2 (0.46) | CD209CA2IGF2RGAACDK1 | |
| SCHEMBL2233863 | 0.81 | CA2 (0.45) | CD209CA2IGF2RGAACDK1 | |
| SCHEMBL1066087 | 0.79 | L3MBTL1 (0.41) | IGF2RGAAPRKD3PRKCGPRKCB | |
| SCHEMBL1458867 | 0.79 | L3MBTL1 (0.41) | IGF2RGAAPRKD3PRKCGPRKCB | |
| SCHEMBL8331449 | 0.79 | L3MBTL1 (0.41) | IGF2RGAAPRKD3PRKCGPRKCB | |
| SCHEMBL9442810 | 0.76 | CA2 (0.47) | CD209CA2IGF2RGAACDK1 | |
| SCHEMBL3896598 | 0.75 | CA2 (0.46) | CD209CA2IGF2RGAACDK1 | |
| SCHEMBL11417663 | 0.75 | CD209 (0.60) | CD209CA2IGF2RGAACDK1 | |
| SCHEMBL11225619 | 0.75 | CD209 (0.60) | CD209CA2IGF2RGAACDK1 | |
| SCHEMBL4155795 | 0.75 | CD209 (0.60) | CD209CA2IGF2RGAACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1978987-A2 | METHODS AND COMPOSITIONS RELATED TO IMPROVING PROPERTIES OF PHARMACOLOGICAL AGENTS TARGETING NERVOUS SYSTEM | University of Utah Research Foundation (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007081792-A2 | METHODS AND COMPOSITIONS RELATED TO IMPROVING PROPERTIES OF PHARMACOLOGICAL AGENTS TARGETING NERVOUS SYSTEM | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2007-07-19 | — | — | WO | disclosed |