SCHEMBL5033239

SCHEMBL5033239

CCCCC=Cc1ccc(CC)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNNC1 P63316 1/20 0.50
ALOX5 P09917 1/20 0.44
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
TUBB1 Q9H4B7 1/20 0.42
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HPGD P15428 2/20 0.40
ALDH1A1 P00352 1/20 0.40
KCNH2 Q12809 2/20 0.39
MAOB P27338 2/20 0.36
HTT P42858 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAOA P21397 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8383292 0.92 TNNC1 (0.58) TNNC1ALOX5PTGS1PTGS2TUBB1
SCHEMBL27892534 0.86 TNNC1 (0.56) TNNC1PTGS1PTGS2LMNASMN1; SMN2
SCHEMBL7241049 0.85 TNNC1 (0.55) TNNC1PTGS1PTGS2LMNAALDH1A1
SCHEMBL7241048 0.85 TNNC1 (0.55) TNNC1PTGS1PTGS2LMNAALDH1A1
SCHEMBL28159433 0.85 TNNC1 (0.48) TNNC1ALOX5PTGS1PTGS2KCNH2
SCHEMBL9096826 0.85 TNNC1 (0.48) TNNC1ALOX5PTGS1PTGS2ALDH1A1
SCHEMBL9802061 0.83 TNNC1 (0.61) TNNC1PTGS1PTGS2LMNAALDH1A1
SCHEMBL9802056 0.83 TNNC1 (0.61) TNNC1PTGS1PTGS2LMNAALDH1A1
SCHEMBL6046924 0.83 TNNC1 (0.55) TNNC1ALDH1A1KCNH2
SCHEMBL7232803 0.82 ALOX5 (0.43) TNNC1ALOX5PTGS1PTGS2TUBB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240182677-A1 Curable Compositions AGC Multi Material America, Inc. 2024-06-06 US disclosed
CN-118047914-A Curable composition AGC多材料美国有限公司 2024-05-17 CN disclosed
CN-116940608-A Curable composition AGC多材料美国有限公司 2023-10-24 CN disclosed
WO-2023164430-A1 CURABLE COMPOSITIONS AGC Multi Material America, Inc. (US) 2023-08-31 WO disclosed
US-20230265275-A1 Curable Compositions AGC Multi Material America, Inc. 2023-08-24 US disclosed
US-7402645-B2 Soluble polyfunctional vinyl aromatic polymer and method of producing the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2008-07-22 US disclosed
US-20070155923-A1 Soluble polyfunctional vinyl aromatic polymer and method of producing the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2007-07-05 US disclosed
US-6900273-B1 Low-hygroscopicity low-birefringence resin compositions, molding material obtained therefrom, sheet or film, and optical part HITACHI CHEMICAL CO., LTD. (JP) 2005-05-31 US disclosed
US-20040220342-A1 Low-hygroscopicity low-birefringence resin compositions, molding material, sheet or film obtained therefrom, and optical part YAMASHITA YUKIHIKO (JP) 2004-11-04 US disclosed
EP-1205517-A1 LOW-HYGROSCOPICITY LOW-BIREFRINGENCE RESIN COMPOSITIONS, MOLDING MATERIAL OBTAINED THEREFROM, SHEET OR FILM, AND OPTICAL PART HITACHI CHEMICAL COMPANY, LTD. (JP) 2002-05-15 EP disclosed