SCHEMBL5033431

SCHEMBL5033431

C=C(C)c1cccc2ccc(CC)cc12

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2A6 P11509 1/20 0.47
SIGMAR1 Q99720 6/20 0.37
GAA P10253 1/20 0.37
PARP1 P09874 1/20 0.36
TRPA1 O75762 1/20 0.36
CDC25B P30305 1/20 0.35
TYMS P04818 1/20 0.35
TP53 P04637 1/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
THPO P40225 1/20 0.35
MTOR P42345 1/20 0.35
MTNR1A P48039 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1978093 0.87 PLAU (0.37) CNR2CYP1A2CYP2D6MTNR1A
SCHEMBL5034603 0.87 CYP1A2 (0.47) CNR2CYP1A2CYP2A6SIGMAR1GAA
SCHEMBL6325416 0.83 CNR2 (0.53) CNR2CYP1A2CYP2A6PARP1CDC25B
SCHEMBL2519050 0.83 MTNR1A (0.38) CNR2TP53MTNR1A
SCHEMBL6323376 0.80 NR4A1 (0.55) CNR2CYP1A2CYP2A6PARP1CDC25B
SCHEMBL8985762 0.78 CNR2 (0.49) CNR2CYP1A2CYP2A6GAAPARP1
SCHEMBL1506783 0.77 MCL1 (0.51) CYP1A2MTNR1A
SCHEMBL10970254 0.76 CNR2 (0.50) CNR2CYP1A2CYP2A6PARP1CDC25B
SCHEMBL27816779 0.76 CNR2 (0.50) CNR2CYP1A2CYP2A6PARP1CDC25B
SCHEMBL20719283 0.76 CYP2A6 (0.41) CYP1A2CYP2A6TYMSCYP2D6MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7402645-B2 Soluble polyfunctional vinyl aromatic polymer and method of producing the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2008-07-22 US disclosed
US-20070155923-A1 Soluble polyfunctional vinyl aromatic polymer and method of producing the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2007-07-05 US disclosed