Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5033431 | 0.87 | CNR2 (0.47) | CYP1A2CYP2A6PARP1SIGMAR1GAA | |
| SCHEMBL5033244 | 0.81 | CYP1A2 (0.44) | CYP1A2CYP2A6PARP1SIGMAR1GAA | |
| SCHEMBL345159 | 0.80 | PTPN1 (0.60) | CYP1A2CYP2A6PARP1TBXAS1GAA | |
| SCHEMBL345117 | 0.78 | DHODH (0.50) | CYP1A2CYP2A6PARP1GAAKDR | |
| SCHEMBL1506774 | 0.77 | TLR8 (0.47) | CYP1A2GAAPTPN1CDC25BCYP2D6 | |
| SCHEMBL10975750 | 0.76 | ALDH1A1 (0.44) | CYP1A2CYP2A6PARP1TBXAS1PTPN1 | |
| SCHEMBL3359160 | 0.75 | CYP1A2 (0.53) | CYP1A2CYP2A6TRPA1 | |
| SCHEMBL9857537 | 0.75 | CNR2 (0.48) | CYP1A2CYP2A6PTPN1CNR2CDC25B | |
| SCHEMBL29563474 | 0.74 | PTK2B (0.55) | CYP1A2CYP2A6PTPN1CDC25BTP53 | |
| SCHEMBL273123 | 0.74 | PTK2B (0.55) | CYP1A2CYP2A6PTPN1CDC25BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402645-B2 | Soluble polyfunctional vinyl aromatic polymer and method of producing the same | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2008-07-22 | — | — | US | disclosed |
| US-20070155923-A1 | Soluble polyfunctional vinyl aromatic polymer and method of producing the same | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2007-07-05 | — | — | US | disclosed |