SCHEMBL503347

SCHEMBL503347

N[C@H](CC1CCCCC1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 5/20 0.49
GRIN3B O60391 5/20 0.49
GRIN1 Q05586 5/20 0.49
GRIN2A Q12879 5/20 0.49
GRIN2B Q13224 5/20 0.49
GRIN2C Q14957 5/20 0.49
GRIN3A Q8TCU5 5/20 0.49
SLC1A3 P43003 3/20 0.49
SLC1A2 P43004 3/20 0.49
SLC1A1 P43005 3/20 0.49
GRIK1 P39086 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43515 1.00 GRIN2D (0.49) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL5980862 1.00 GRIN2D (0.49) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL5605868 1.00 GRIN2D (0.49) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2652715 1.00 GRIN2D (0.49) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2651847 1.00 GRIN2D (0.49) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL123134 1.00 GRIN2D (0.49) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL971796 0.98 GRIN2D (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Water SCHEMBL2651079 0.98 GRIN2D (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Water SCHEMBL29155398 0.98 GRIN2D (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL971795 0.98 GRIN2D (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 597 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001915-A1 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS INC (US) 2026-01-01 US claimed
US-20250361274-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT PEPTIDREAM INC. (JP) 2025-11-27 US claimed
CN-120152725-A Methods of treating obesity using MC4R agonists 节奏制药公司 2025-06-13 CN claimed
EP-4554607-A2 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST Rhythm Pharmaceuticals, Inc. (US) 2025-05-21 EP claimed
EP-4541805-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT PeptiDream Inc. (JP) 2025-04-23 EP claimed
US-20240368224-A1 BICYCLIC PEPTIDYL PAN-RAS INHIBITORS OHIO STATE INNOVATION FOUNDATION 2024-11-07 US claimed
US-20240317803-A1 BCL9 PEPTIDES AND VARIANTS THEREOF WNTRX PHARMACEUTICALS INC. 2024-09-26 US claimed
EP-4274838-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BICYCLETX LTD (GB) 2024-09-25 EP claimed
CN-118496313-A Calcium sensitive receptor agonist compounds and uses thereof 北京拓界生物医药科技有限公司 2024-08-16 CN claimed
EP-4388124-A1 SELECTIVE MEASUREMENT OF HUMAN FACTOR VIII Takeda Pharmaceutical Company Limited (JP) 2024-06-26 EP claimed
WO-2005100385-A2 COMPOUNDS THAT BLOCK THE C5A RECEPTOR AND THEIR USE IN THERAPY ALLIGATOR BIOSCIENCE AB (PUBL) (SE) 2005-10-27 WO claimed
EP-1586583-A2 Compounds that block C5a complement receptor and their use in therapy Alligator Bioscience AB (publ) (SE) 2005-10-19 EP claimed
WO-2003006048-A1 COMBINATION OF CHIPS (CHEMOTAXIS INHIBITING PROTEIN FROM STAPHYLOCOCCUS AUREUS)-BASED COMPOUNDS JARI PHARMACEUTICALS B.V. (NL) 2003-01-23 WO claimed
US-6495336-B1 OLIGOPEPTIDE DERIVATIVES WHOSE C-TERMINAL AMINO ACID IS ARGININE WHICH IS LINKED TO THE REMAINDER OF AN ELECTROACTIVE ANILINE OR AMINOQUINILONE; SUBSTRATE FOR QUANTITATIVELY DETERMINING ENZYMES, ESPECIALLY THROMBIN, IN BLOOD PENTAPHARM AG (CH) 2002-12-17 US claimed
EP-1157029-A1 OLIGOPEPTIDE DERIVATIVES FOR THE ELECTROCHEMICAL MEASUREMENT OF PROTEASE ACTIVITY Pentapharm AG (CH) 2001-11-28 EP claimed
WO-2000050446-A1 OLIGOPEPTIDE DERIVATIVES FOR THE ELECTROCHEMICAL MEASUREMENT OF PROTEASE ACTIVITY PENTAPHARM AG (CH) 2000-08-31 WO claimed
EP-1025127-A1 MSH-RECEPTOR SUBTYPE SELECTIVE CYCLIC PEPTIDES Wapharm AB (SE) 2000-08-09 EP claimed
EP-1023324-A1 TRIVALENT THROMBIN INHIBITOR NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2000-08-02 EP claimed
WO-1999019356-A1 TRIVALENT THROMBIN INHIBITOR NATIONAL RESEARCH COUNCIL OF CANADA (CA) 1999-04-22 WO claimed
WO-1998037097-A1 MSH-RECEPTOR SUBTYPE SELECTIVE CYCLIC PEPTIDES WAPHARM AB (SE) 1998-08-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240317803-A1 BCL9 PEPTIDES AND VARIANTS THEREOF BCL9, BCL9L, BCL3 GRIN2D 4702/4885GRIN3B 4728/4885GRIN1 4861/4885
US-20260001915-A1 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST MC4R, NPY4R, MC3R GRIN2D 358/4885GRIN3B 162/4885GRIN1 555/4885
US-20240368224-A1 BICYCLIC PEPTIDYL PAN-RAS INHIBITORS KRAS, HRAS, NRAS GRIN2D 4825/4885GRIN3B 4347/4885GRIN1 4422/4885
US-20250361274-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT BMP4, BMP1, BMPR2 GRIN2D 3943/4885GRIN3B 3171/4885GRIN1 3937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.