SCHEMBL503375

SCHEMBL503375

c1ccc(-c2c3cc4c5ccccc5c5cccc(c3c(-c3ccccc3)c3c6cccc7cccc(c23)c76)c54)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.44
ALDH1A1 P00352 4/20 0.44
HPGD P15428 4/20 0.44
HSD17B10 Q99714 3/20 0.44
THRB P10828 1/20 0.44
ERBB2 P04626 1/20 0.37
FYN P06241 1/20 0.37
MAOA P21397 1/20 0.37
ACHE P22303 1/20 0.37
AHR P35869 1/20 0.37
ESR1 P03372 5/20 0.37
ESR2 Q92731 4/20 0.37
KDM4E B2RXH2 3/20 0.33
TSHR P16473 2/20 0.33
MAPT P10636 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13101555 0.88 CYP1A2 (0.39) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL4979724 0.86 ALDH1A1 (0.45) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL13090404 0.86 SMN1; SMN2 (0.37) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL10015394 0.85 CYP1A2 (0.33) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL17119049 0.85 CA1 (0.38) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL23348952 0.84 CYP1A2 (0.41) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL13101553 0.84 CYP11B1 (0.49) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL3437829 0.84 CYP1A2 (0.41) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL13090418 0.84
SCHEMBL23348936 0.84 CYP1A2 (0.37) CYP1A2ALDH1A1HPGDHSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230047477-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-16 US disclosed
US-20230042023-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-09 US disclosed
US-11552252-B1 2023-01-10 US disclosed
US-20220285625-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-09-08 US disclosed
US-9315460-B2 Organic compound, light-emitting device, and image display apparatus CANON KABUSHIKI KAISHA (JP) 2016-04-19 US disclosed
EP-2421809-B1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS CANON KK (JP) 2015-09-02 EP disclosed
US-8940413-B2 Organic compound having acenaphtho[1,2-k]benzo[e]acephenanthrene derivative, light-emitting device, and image display apparatus CANON KABUSHIKI KAISHA (JP) 2015-01-27 US disclosed
US-20140374738-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS CANON KK (JP) 2014-12-25 US disclosed
US-8293384-B2 Organic compound, light-emitting device, and image display apparatus CANON KABUSHIKI KAISHA (JP) 2012-10-23 US disclosed
EP-2243761-B1 Phenanthrene derivatives, light-emitting device and image display apparatus using the same CANON KK (JP) 2012-08-22 EP disclosed
US-20120025183-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-02-02 US disclosed
US-20100270914-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-10-28 US disclosed
EP-2243761-A1 Phenanthrene derivatives, light-emitting device and image display apparatus using the same Canon Kabushiki Kaisha (JP) 2010-10-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120025183-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS ACE, ACE2, AGTR1 CYP1A2 182/4885ALDH1A1 218/4885HPGD 2925/4885
US-20100270914-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS ACE2, ACE, AGTR1 CYP1A2 50/4885ALDH1A1 100/4885HPGD 2390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.