Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19599666 | 0.87 | LTA4H (0.49) | TSHRALDH1A1RECQLTDP1IDO1 | |
| SCHEMBL177923 | 0.83 | TSHR (0.67) | TSHRALDH1A1TDP1IDO1AGXT | |
| Alcohol SCHEMBL5269265 | 0.81 | TSHR (0.52) | TSHRALDH1A1TDP1IDO1AGXT | |
| SCHEMBL4363419 | 0.80 | TSHR (0.63) | TSHRALDH1A1TDP1IDO1AGXT | |
| Water SCHEMBL28419682 | 0.80 | TSHR (0.63) | TSHRALDH1A1TDP1IDO1AGXT | |
| SCHEMBL23340 | 0.79 | TSHR (0.64) | TSHRALDH1A1RECQLTDP1IDO1 | |
| Phenol SCHEMBL27287307 | 0.79 | TDP1 (0.52) | TSHRALDH1A1RECQLTDP1IDO1 | |
| SCHEMBL3612659 | 0.79 | TSHR (0.50) | TSHRALDH1A1TDP1IDO1AGXT | |
| SCHEMBL30425799 | 0.79 | TSHR (0.64) | TSHRALDH1A1RECQLTDP1IDO1 | |
| Bicarbonate SCHEMBL9066694 | 0.78 | ALDH1A1 (0.58) | TSHRALDH1A1TDP1IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164381-A | Pharmaceutical compositions and methods relating to otic therapeutic agents | 频率医疗公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2014057687-A1 | ANTIBODY-DRUG CONJUGATE | 第一三共株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |
| EP-1994087-A2 | POLYMER COMPOSITES, POLYMER NANOCOMPOSITES AND METHODS | Chaiko, David J. (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007095292-A2 | POLYMER COMPOSITES, POLYMER NANOCOMPOSITES AND METHODS | CHAIKO DAVID J (US) | 2007-08-23 | — | — | WO | disclosed |