Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17046664 | 0.84 | — | — | |
| SCHEMBL4159446 | 0.83 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL15324353 | 0.83 | — | — | |
| SCHEMBL9817276 | 0.79 | — | — | |
| SCHEMBL199742 | 0.77 | — | — | |
| SCHEMBL5179216 | 0.74 | KIF11 (0.35) | ALDH1A1 | |
| SCHEMBL900856 | 0.73 | KDM4E (0.36) | KDM4EALDH1A1TDP1PTPN1PTPRZ1 | |
| SCHEMBL980439 | 0.73 | — | — | |
| SCHEMBL6715685 | 0.72 | — | — | |
| SCHEMBL6485155 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 884 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117797146-A | SARM1 enzyme activity inhibitors and their use in neurodegenerative diseases | 科辉智药生物科技（无锡）有限公司 | 2024-04-02 | — | — | CN | claimed |
| US-20230414581-A1 | SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF IN NEURODEGENERATIVE DISEASES | ARTIVILA BIOPHARMA (CN) | 2023-12-28 | — | — | US | claimed |
| CN-117024430-A | Bipyrimidine fluorene compound, organic electroluminescent element and consumer product | 浙江八亿时空先进材料有限公司 | 2023-11-10 | — | — | CN | claimed |
| US-20230131260-A1 | SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | claimed |
| CN-114907361-A | Trimeric heterocyclic derivative and application thereof | 北京八亿时空液晶科技股份有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-114470215-A | SARM1 enzyme activity inhibitor and application thereof in neurodegenerative diseases | 北京科辉智药生物科技有限责任公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114256431-A | Material for organic electroluminescent element, and consumer product | 上海八亿时空先进材料有限公司 | 2022-03-29 | — | — | CN | claimed |
| CN-114213409-A | Material for organic electroluminescent element, and consumer product | 上海八亿时空先进材料有限公司 | 2022-03-22 | — | — | CN | claimed |
| US-11274083-B2 | Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents | SYNGENTA CROP PROTECTION AG (CH) | 2022-03-15 | — | — | US | claimed |
| EP-3728237-B1 | SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-09 | — | — | EP | claimed |
| EP-0643707-A1 | THIADIAZOLINES AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1995-03-22 | — | — | EP | claimed |
| WO-1993024474-A1 | THIADIAZOLINES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-09 | — | — | WO | claimed |
| EP-0550900-A1 | Herbicidal and plant-nematocidal compositions based on mercaptonicotinic acid derivatives | BAYER AG (DE) | 1993-07-14 | — | — | EP | claimed |
| EP-0127062-A2 | Alkylene-bis-heterocyclyl biguanides | BAYER AG (DE) | 1984-12-05 | — | — | EP | claimed |
| US-4482712-A | FUNGICIDES; HERBICIDES; PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1984-11-13 | — | — | US | claimed |
| EP-0010420-B1 | PYRIDYL-SUBSTITUTED THIAZOLIDINE AND 1,3-THIAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AGRICULTURAL COMPOSITIONS CONTAINING SAID DERIVATIVES AND METHODS FOR REGULATING PLANT GROWTH AND PROTECTING PLANTS FROM FUNGI | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | claimed |
| US-4271186-A | Stilbene compounds and insecticidal/acaricidal compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-02 | — | — | US | claimed |
| EP-0010420-A1 | Pyridyl-substituted thiazolidine and 1,3-thiazine derivatives, processes for their preparation, agricultural compositions containing said derivatives and methods for regulating plant growth and protecting plants from fungi | ELI LILLY AND COMPANY (US) | 1980-04-30 | — | — | EP | claimed |
| US-4017623-A | Esters of 2-[(4-quinolyl)amino]-benzoic acids in analgesic and anti-inflammatory compositions | SYNTHELABO (FR) | 1977-04-12 | — | — | US | claimed |
| US-3935229-A | ANALGESIC, ANTIINFLAMMATORY | SYNTHELABO (FR) | 1976-01-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274083-B2 | Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents | UNG, TYMP, TYMS | KDM4E 1634/4885ALDH1A1 133/4885TDP1 207/4885 |
| US-20230414581-A1 | SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF IN NEURODEGENERATIVE DISEASES | SARM1, BACE1, GAA | KDM4E 2340/4885ALDH1A1 1654/4885TDP1 114/4885 |
| US-20230131260-A1 | SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | UNG, TYMP, TYMS | KDM4E 1497/4885ALDH1A1 170/4885TDP1 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.