Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9388697 | 0.79 | — | — | |
| SCHEMBL8357519 | 0.76 | TSHR (0.41) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL302981 | 0.76 | TSHR (0.55) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL1647546 | 0.73 | TSHR (0.52) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL23094079 | 0.71 | TSHR (0.57) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL8639963 | 0.71 | TSHR (0.57) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL10704544 | 0.71 | TSHR (0.50) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL8765586 | 0.71 | TSHR (0.57) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL323671 | 0.71 | TSHR (0.57) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL28862986 | 0.70 | THRB (0.42) | TSHRMEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999167-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | Novolen Technology Holdings, C.V. (NL) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007106348-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-09-20 | — | — | WO | disclosed |
| US-20070213204-A1 | Ziegler-Natta catalyst with in situ-generated donor | NOVOLEN TECHNOLOGY HOLDINGS C.V. | 2007-09-13 | — | — | US | disclosed |