Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18668677 | 0.82 | HTR1A (0.53) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL4732810 | 0.81 | MTNR1A (0.46) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL4730904 | 0.80 | SMYD3 (0.52) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL4734530 | 0.80 | SMYD3 (0.56) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL1545216 | 0.80 | SMYD3 (0.52) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL1150614 | 0.79 | GAA (0.69) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL29831598 | 0.79 | GAA (0.69) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL1531662 | 0.79 | GAA (0.69) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| SCHEMBL444953 | 0.79 | GAA (0.69) | SMYD3MTNR1AHTR1AHTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL11050093 | 0.77 | GAA (0.67) | SMYD3MTNR1AHTR1AHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888575-A2 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | Hydra Biosciences, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122156-A2 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2006-11-16 | — | — | WO | disclosed |