Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.54 |
| ▸ | PPARA | Q07869 | 16/20 | 0.54 |
| ▸ | PPARG | P37231 | 11/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031896 | 0.92 | PPARD (0.60) | PPARDPPARAPPARG | |
| SCHEMBL5031721 | 0.85 | SORT1 (0.44) | PPARDPPARAPPARG | |
| SCHEMBL5036999 | 0.84 | PPARD (0.47) | PPARDPPARAPPARG | |
| SCHEMBL5032904 | 0.83 | PPARA (0.46) | PPARDPPARAPPARG | |
| SCHEMBL5031789 | 0.82 | PPARG (0.47) | PPARDPPARAPPARG | |
| SCHEMBL5140591 | 0.82 | PPARG (0.47) | PPARDPPARAPPARG | |
| SCHEMBL5139221 | 0.82 | PPARG (0.47) | PPARDPPARAPPARG | |
| SCHEMBL5031809 | 0.82 | ALDH1A1 (0.37) | PPARDPPARAPPARG | |
| SCHEMBL5139800 | 0.82 | ALDH1A1 (0.37) | PPARDPPARAPPARG | |
| SCHEMBL5032880 | 0.82 | HTT (0.46) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-20050014833-A1 | Cyclic compound and ppar agonist | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| EP-1452521-A1 | CYCLIC COMPOUND AND PPAR AGONIST | Eisai Co., Ltd. (JP) | 2004-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014833-A1 | Cyclic compound and ppar agonist | PPARA, PPARG, PPARD | PPARD 3/4885PPARA 1/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.