Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 10/20 | 0.41 |
| ▸ | NOS1 | P29475 | 9/20 | 0.41 |
| ▸ | NOS3 | P29474 | 6/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.37 |
| ▸ | TBKBP1 | A7MCY6 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | STK10 | O94804 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | YES1 | P07947 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831915 | 0.87 | KDM4E (0.42) | NOS2NOS1NOS3FGFR3CYP2C9 | |
| SCHEMBL2830885 | 0.85 | NOS1 (0.42) | NOS2NOS1NOS3FGFR3CYP2C9 | |
| SCHEMBL2833899 | 0.85 | NOS1 (0.47) | NOS2NOS1NOS3FGFR3CYP2C9 | |
| SCHEMBL2831824 | 0.84 | MAP4K1 (0.49) | NOS2NOS1NOS3FGFR3CYP2C9 | |
| SCHEMBL2835191 | 0.84 | KDM4E (0.43) | NOS2NOS1NOS3FGFR3CYP2C9 | |
| SCHEMBL2832530 | 0.81 | MAP4K1 (0.47) | NOS2NOS1NOS3FGFR3CYP2C9 | |
| SCHEMBL2836472 | 0.81 | NOS2 (0.42) | NOS2NOS1NOS3FGFR3CYP2C9 | |
| SCHEMBL2831963 | 0.80 | NOS1 (0.40) | NOS2NOS1NOS3FGFR3CYP2C9 | |
| SCHEMBL2832956 | 0.79 | NOS2 (0.39) | NOS2NOS1NOS3FGFR3CYP2C9 | |
| SCHEMBL2832542 | 0.77 | NOS2 (0.48) | NOS2NOS1NOS3FGFR3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670796-B1 | IMIDAZOPYRIDINE-DERIVATIVES AS INDUCIBLE NO-SYNTHASE INHIBITORS | NYCOMED GMBH (DE) | 2008-06-25 | — | — | EP | claimed |