Hydrochloric Acid

Hydrochloric Acid

SCHEMBL503460

CO[Si](CCCn1cc[n+](C)c1)(OC)OC.[Cl-]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.51
MEN1 O00255 1/20 0.51
APAF1 O14727 1/20 0.51
NPC1 O15118 1/20 0.51
PLA2G1B P04054 1/20 0.51
HSP90AA1 P07900 1/20 0.51
MAPT P10636 1/20 0.51
MAPK1 P28482 1/20 0.51
HTT P42858 1/20 0.51
RAB9A P51151 1/20 0.51
KMT2A Q03164 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
ATG4B Q9Y4P1 1/20 0.51
PON1 P27169 1/20 0.34
FDPS P14324 2/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL537081 0.98 SMN1; SMN2 (0.53) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
Iodide SCHEMBL3733345 0.97 SMN1; SMN2 (0.51) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
SCHEMBL16433374 0.86 MEN1 (0.45) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
Hydrochloric Acid SCHEMBL508922 0.84 MEN1 (0.53) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
SCHEMBL16724670 0.83 MEN1 (0.42) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
SCHEMBL669979 0.82 SMN1; SMN2 (0.54) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
Hydrochloric Acid SCHEMBL30360159 0.81 MEN1 (0.35) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
Hydrochloric Acid SCHEMBL503686 0.81 MEN1 (0.38) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
Hydrochloric Acid SCHEMBL6284737 0.80 MEN1 (0.55) SMN1; SMN2MEN1APAF1NPC1PLA2G1B
SCHEMBL17706457 0.79 SMN1; SMN2 (0.58) SMN1; SMN2MEN1APAF1NPC1PLA2G1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9966644-B2 Cathode, lithium air battery including the same, and method of preparing the cathode SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-08 US claimed
US-20160079590-A1 CATHODE, LITHIUM AIR BATTERY INCLUDING THE SAME, AND METHOD OF PREPARING THE CATHODE SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-03-17 US claimed
US-11938467-B2 Catalyst system for producing cyclic carbonates and method related thereto PTT EXPLORATION AND PRODUCTION PUBLIC COMPANY LIMITED (TH) 2024-03-26 US disclosed
US-11938468-B2 Catalyst system for producing cyclic carbonates and method related thereto PTT EXPLORATION AND PRODUCTION PUBLIC COMPANY LIMITED (TH) 2024-03-26 US disclosed
EP-3013747-B1 METHOD FOR PREPARING A COMPOSITION COMPRISING FUNCTIONALISED MINERAL PARTICLES AND CORRESPONDING COMPOSITION CENTRE NAT RECH SCIENT (FR) 2024-01-24 EP disclosed
CN-112912176-B Catalyst systems for the production of cyclic carbonates and related methods PTT勘探与生产公共有限公司 2023-11-17 CN disclosed
CN-113164940-B Catalyst systems for the production of cyclic carbonates and related methods PTT勘探与生产公共有限公司 2023-09-29 CN disclosed
EP-3852921-B1 CATALYST SYSTEM FOR PRODUCING CYCLIC CARBONATES AND METHOD RELATED THERETO PTT EXPLORATION AND PRODUCTION PUBLIC COMPANY LTD (TH) 2023-06-07 EP disclosed
US-11618827-B2 Method for preparing a composition comprising functionalised mineral particles and corresponding composition CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2023-04-04 US disclosed
EP-3852920-B1 CATALYST SYSTEM FOR PRODUCING CYCLIC CARBONATES AND METHOD RELATED THERETO PTT EXPLORATION AND PRODUCTION PUBLIC COMPANY LTD (TH) 2022-09-07 EP disclosed
US-20220220316-A1 METHOD FOR PREPARING A COMPOSITION COMPRISING FUNCTIONALISED MINERAL PARTICLES AND CORRESPONDING COMPOSITION UNIVERSITE PAUL SABATIER TOULOUSE III (FR) 2022-07-14 US disclosed
US-20160079590-A1 CATHODE, LITHIUM AIR BATTERY INCLUDING THE SAME, AND METHOD OF PREPARING THE CATHODE SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-03-17 US disclosed
EP-2554249-B1 COMPOSITE SEMIPERMEABLE MEMBRANE TORAY INDUSTRIES (JP) 2016-02-10 EP disclosed
US-20150133290-A1 METHOD FOR PREPARING A HYDROGEL COMPRISING SILICO-METALLIC MINERAL PARTICLES AND HYDROGEL CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N. R.S.) (FR) 2015-05-14 US disclosed
US-8739977-B2 Composite semipermeable membrane and method for producing the same TORAY INDUSTRIES, INC. (JP) 2014-06-03 US disclosed
US-8672143-B2 Composite semipermeable membrane TORAY INDUSTRIES, INC. (JP) 2014-03-18 US disclosed
US-20130032530-A1 COMPOSITE SEMIPERMEABLE MEMBRANE TORAY INDUSTRIES, INC. (JP) 2013-02-07 US disclosed
EP-2554249-A1 COMPOSITE SEMIPERMEABLE MEMBRANE Toray Industries, Inc. (JP) 2013-02-06 EP disclosed
EP-2415515-A1 COMPOSITE SEMIPERMEABLE MEMBRANE AND PROCESS FOR PRODUCTION THEREOF Toray Industries, Inc. (JP) 2012-02-08 EP disclosed
US-20120024778-A1 COMPOSITE SEMIPERMEABLE MEMBRANE AND METHOD FOR PRODUCING THE SAME TORAY INDUSTRIES, INC. (JP) 2012-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11938468-B2 Catalyst system for producing cyclic carbonates and method related thereto SCO2, CCNO, CYCS SMN1; SMN2 4855/4885MEN1 323/4885APAF1 4248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.