SCHEMBL503466

SCHEMBL503466

O=C(O)CCCCCC(=O)CC(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.67
LMNA P02545 3/20 0.67
NFKB1 P19838 1/20 0.67
PMP22 Q01453 1/20 0.67
KMT2A Q03164 3/20 0.58
MAPT P10636 1/20 0.58
GPR84 Q9NQS5 8/20 0.55
FFAR1 O14842 2/20 0.55
FFAR4 Q5NUL3 2/20 0.55
FOLH1 Q04609 1/20 0.55
SLC22A6 Q4U2R8 2/20 0.53
PPARG P37231 6/20 0.52
PPARD Q03181 6/20 0.52
PPARA Q07869 6/20 0.52
HDAC11 Q96DB2 5/20 0.52
ALDH1A1 P00352 3/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
MEN1 O00255 2/20 0.52
FABP4 P15090 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10861269 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22KMT2A
SCHEMBL503360 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22KMT2A
SCHEMBL11622180 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22KMT2A
SCHEMBL503966 0.97 LMNA (0.65) TSHRLMNANFKB1PMP22KMT2A
SCHEMBL6265240 0.94 TSHR (0.56) TSHRLMNANFKB1PMP22KMT2A
SCHEMBL11438692 0.94 TSHR (0.56) TSHRLMNANFKB1PMP22KMT2A
SCHEMBL8751902 0.94 TSHR (0.56) TSHRLMNANFKB1PMP22KMT2A
SCHEMBL12568558 0.92 TSHR (0.71) TSHRLMNANFKB1PMP22KMT2A
SCHEMBL284957 0.92 SLC22A6 (0.65) TSHRLMNANFKB1PMP22KMT2A
SCHEMBL9185822 0.91 LMNA (0.53) TSHRLMNANFKB1PMP22KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8435718-B2 Upper layer-forming composition and photoresist patterning method JSR CORPORATION (JP) 2013-05-07 US disclosed
EP-1950610-B1 IMMERSION LITHOGRAPHIC COMPOSITION FOR FORMING UPPER FILM AND METHOD FOR FORMING PHOTORESIST PATTERN JSR CORP (JP) 2012-05-02 EP disclosed
US-20120028198-A1 UPPER LAYER-FORMING COMPOSITION AND PHOTORESIST PATTERNING METHOD JSR CORPORATION (JP) 2012-02-02 US disclosed
US-20100003615-A1 UPPER LAYER-FORMING COMPOSITION AND PHOTORESIST PATTERNING METHOD JSR CORPORATION (JP) 2010-01-07 US disclosed
EP-1950610-A1 COMPOSITION FOR FORMING UPPER FILM AND METHOD FOR FORMING PHOTORESIST PATTERN JSR Corporation (JP) 2008-07-30 EP disclosed
EP-1230225-A2 PHARMACEUTICALLY ACTIVE 4-SUBSTITUTED PYRIMIDINE DERIVATIVES ELI LILLY AND COMPANY (US) 2002-08-14 EP disclosed
WO-2001032632-A2 PHARMACEUTICALLY ACTIVE 4-SUBSTITUTED PYRIMIDINE DERIVATIVES ELI LILLY AND COMPANY (US) 2001-05-10 WO disclosed
EP-0610439-B1 PYRIMIDOCYCLOALKANES AS ANGIOTENSIN II ANTAGONISTS AMERICAN HOME PROD (US) 1999-12-15 EP disclosed
EP-0610439-A1 PYRIMIDOCYCLOALKANES AS ANGIOTENSIN II ANTAGONISTS AMERICAN HOME PRODUCTS CORPORATION (US) 1994-08-17 EP disclosed
US-5234936-A Treating hypertension, congestive heart failure, hyperlipidemia and hypercholesterolemia AMERICAN HOME PRODUCTS CORPORATION (US) 1993-08-10 US disclosed
WO-1993008171-A1 PYRIMIDOCYCLOALKANES AS ANGIOTENSIN II ANTAGONISTS AMERICAN HOME PRODUCTS CORPORATION (US) 1993-04-29 WO disclosed
EP-0157567-B1 CARBOXY-CONTAINING ESTER PRODRUGS OF CORTICOSTEROIDS THE UPJOHN COMPANY (US) 1989-11-29 EP disclosed
US-4588718-A ANTIINFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1986-05-13 US disclosed
EP-0157567-A2 Carboxy-containing ester prodrugs of corticosteroids THE UPJOHN COMPANY (US) 1985-10-09 EP disclosed