Sugi Predict

Sugi Predict / Compounds / SCHEMBL284957

SCHEMBL284957

SCHEMBL284957

O=C(O)CCCC(=O)CC(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC22A6 Q4U2R8 1/20 0.65
▸ LMNA P02545 4/20 0.56
▸ TSHR P16473 3/20 0.53
▸ NFKB1 P19838 2/20 0.53
▸ PMP22 Q01453 1/20 0.53
▸ FOLH1 Q04609 1/20 0.50
▸ KMT2A Q03164 2/20 0.48
▸ MAPT P10636 1/20 0.48
▸ CAMK2A Q9UQM7 1/20 0.48
▸ EGLN1 Q9GZT9 2/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ KDM6B O15054 1/20 0.46
▸ KDM5C P41229 1/20 0.46
▸ PHF8 Q9UPP1 1/20 0.46
▸ KDM2A Q9Y2K7 1/20 0.46
▸ GABRR3 A8MPY1 1/20 0.46
▸ GABRP O00591 1/20 0.46
▸ GABRD O14764 1/20 0.46
▸ HDAC3 O15379 1/20 0.46
▸ GABBR2 O75899 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3968413 0.95 SLC22A6 (0.58) SLC22A6LMNATSHRNFKB1PMP22
SCHEMBL503966 0.94 LMNA (0.65) SLC22A6LMNATSHRNFKB1PMP22
SCHEMBL9418710 0.94 SLC22A6 (0.53) SLC22A6LMNATSHRNFKB1PMP22
SCHEMBL10861269 0.92 TSHR (0.67) SLC22A6LMNATSHRNFKB1PMP22
SCHEMBL503466 0.92 TSHR (0.67) SLC22A6LMNATSHRNFKB1PMP22
SCHEMBL503360 0.92 TSHR (0.67) SLC22A6LMNATSHRNFKB1PMP22
SCHEMBL11622180 0.92 TSHR (0.67) SLC22A6LMNATSHRNFKB1PMP22
SCHEMBL12568553 0.91 SLC22A6 (0.69) SLC22A6LMNATSHRNFKB1PMP22
SCHEMBL9185822 0.88 LMNA (0.53) SLC22A6LMNATSHRNFKB1PMP22
SCHEMBL8751902 0.85 TSHR (0.56) SLC22A6LMNATSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022727-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA INC (US) 2023-01-26 — — US claimed
CN-110483301-A A kind of preparation method of 2- oxo-pentane -1,5- dicarboxylate SHANGHAI RAISE CHEMICAL TECH CO LTD 2019-11-22 — — CN claimed
US-20190330670-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2019-10-31 — — US claimed
CN-108219176-A A kind of preparation method of resistance to oxidation plastic article 安徽兴乐健身器材有限公司 2018-06-29 — — CN claimed
CN-107267110-A A kind of binding agent on magnetic liner plate of ball mill 马鞍山起劲磁塑科技有限公司 2017-10-20 — — CN claimed
US-20130303723-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2013-11-14 — — US claimed
WO-2012177721-A1 MICROORGANISMS FOR PRODUCING 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2012-12-27 — — WO claimed
EP-2427544-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID Genomatica, Inc. (US) 2012-03-14 — — EP claimed
US-20100317069-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2010-12-16 — — US claimed
WO-2010129936-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2010-11-11 — — WO claimed
US-12577591-B2 Microorganisms and methods for increasing co-factors GENOMATICA, INC. (US) 2026-03-17 — — US disclosed
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES AGAIN BIO APS (DK) 2026-01-29 — — US disclosed
US-12503711-B2 Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism GENOMATICA, INC. (US) 2025-12-23 — — US disclosed
CN-114728871-B Microorganisms and methods for reducing byproducts 基因组股份公司 2024-12-27 — — CN disclosed
US-20240182935-A1 METHOD OF PRODUCING & PROCESSING DIAMINES AGAIN BIO APS (DK) 2024-06-06 — — US disclosed
US-4473704-A ANALGESICS, ANTIEMETICS PFIZER INC. (US) 1984-09-25 — — US disclosed
EP-0090526-A1 Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta(1)phenanthrenes, decahydro-1H-pyrido(1,2-f)phenanthridines and decahydropyrrolo(1,2-f)phenanthridines as CNS agents PFIZER INC. (US) 1983-10-05 — — EP disclosed
EP-0090516-A1 Substituted hexahydropyrrolo(1,2-a)-quinoline, hexahydro-1H-pyrido(1,2-a)-quinoline, hexahydrobenzo(3)indene and octahydrophenanthrene CNS agents PFIZER INC. (US) 1983-10-05 — — EP disclosed
EP-0073711-A1 Salts of 2-oxopentane-1,5-dicarboxylic acid, their preparation and pharmaceutical preparations containing these salts S.A. DAUTREVILLE ET LEBAS (Société Anonyme) (FR) 1983-03-09 — — EP disclosed
US-3907846-A Preparation of substituted decenoic acids LILLY INDUSTRIES LTD 1975-09-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES DDC, DAO, ODC1 SLC22A6 2092/4885LMNA 2536/4885TSHR 3382/4885
US-12577591-B2 Microorganisms and methods for increasing co-factors ABAT, HADHB, MMAB SLC22A6 1238/4885LMNA 1752/4885TSHR 4263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.