Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462351 | 0.83 | MAOB (0.46) | MAOBMAOACYP2A6PTPRCPTPN1 | |
| SCHEMBL8481860 | 0.83 | MAOB (0.62) | MAOBMAOAKDM4ECHRM2CHRM4 | |
| SCHEMBL8179409 | 0.83 | MAOB (0.48) | MAOBMAOACYP2A6KDM4ETSHR | |
| SCHEMBL11937479 | 0.81 | MAOB (0.47) | MAOBMAOACYP2A6PTPRCPTPN1 | |
| SCHEMBL7437915 | 0.79 | MAOB (0.42) | MAOBMAOAHTR2CALOX5RAB9A | |
| SCHEMBL12854020 | 0.79 | MAOB (0.71) | MAOBMAOAPTPRCPTPN1KDM4E | |
| SCHEMBL61411 | 0.79 | MAOB (0.71) | MAOBMAOAPTPRCPTPN1KDM4E | |
| SCHEMBL19221456 | 0.77 | MAOB (0.44) | MAOBMAOACYP2A6PTPRCPTPN1 | |
| SCHEMBL7440252 | 0.77 | MAOB (0.46) | MAOBMAOAPRKCQPRKCD | |
| SCHEMBL27370060 | 0.77 | FFAR1 (0.42) | MAOBMAOAALOX5PRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689732-A4 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | UNIV NORTH CAROLINA (US) | 2008-10-22 | — | — | EP | claimed |
| US-20080221191-A1 | Cationic substituted benzofurans as antimicrobial agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-11 | — | — | US | claimed |
| EP-1689732-A2 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | The University of North Carolina at Chapel Hill (US) | 2006-08-16 | — | — | EP | claimed |
| US-20050197378-A1 | Cationic substituted benzofurans as antimicrobial agents | TIDWELL RICHARD R (US) | 2005-09-08 | — | — | US | claimed |
| WO-2005055935-A2 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-06-23 | — | — | WO | claimed |
| EP-1689732-A4 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | UNIV NORTH CAROLINA (US) | 2008-10-22 | — | — | EP | disclosed |
| US-20080221191-A1 | Cationic substituted benzofurans as antimicrobial agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-11 | — | — | US | disclosed |
| US-7417158-B2 | Mycobacterium tuberculosis infection; protozoan pathogens; fungal pathogens | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2008-08-26 | — | — | US | disclosed |
| US-20080114047-A1 | Cationic substituted benzofurans as antimicrobial agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-05-15 | — | — | US | disclosed |
| EP-1689732-A2 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | The University of North Carolina at Chapel Hill (US) | 2006-08-16 | — | — | EP | disclosed |
| US-20050197378-A1 | Cationic substituted benzofurans as antimicrobial agents | TIDWELL RICHARD R (US) | 2005-09-08 | — | — | US | disclosed |
| WO-2005055935-A2 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114047-A1 | Cationic substituted benzofurans as antimicrobial agents | BET1, ARG2, BRDT | MAOB 2348/4885MAOA 2700/4885CYP2A6 4517/4885 |
| US-20050197378-A1 | Cationic substituted benzofurans as antimicrobial agents | BET1, ARG2, BRDT | MAOB 2348/4885MAOA 2700/4885CYP2A6 4517/4885 |
| US-20080221191-A1 | Cationic substituted benzofurans as antimicrobial agents | BET1, ARG2, BRDT | MAOB 2348/4885MAOA 2700/4885CYP2A6 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.