SCHEMBL5035128

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5032569	0.88	DPP4 (0.46)	CYP3A4NPC1KDM4EMEN1KMT2A
	SCHEMBL14190164	0.88	CYP3A4 (0.45)	CYP3A4NPC1KDM4ESMN1; SMN2NPSR1
	SCHEMBL5034751	0.88	CYP3A4 (0.47)	CYP3A4NPC1KDM4ESMN1; SMN2NPSR1
	SCHEMBL14190180	0.86	CDK8 (0.44)	CYP3A4NPC1TP53GAAMAPK1
	SCHEMBL5039076	0.86	CYP3A4 (0.39)	C5AR1CYP3A4NPC1CCKARCCKBR
	SCHEMBL5038953	0.86	CYP3A4 (0.46)	CYP3A4NPC1SMN1; SMN2MEN1KMT2A
	SCHEMBL5032541	0.86	CYP3A4 (0.52)	CYP3A4NPC1KDM4ECNR1SMN1; SMN2
	SCHEMBL5035888	0.85	CYP3A4 (0.45)	CYP3A4NPC1CNR1SMN1; SMN2MEN1
	SCHEMBL5034860	0.83	CYP3A4 (0.47)	CYP3A4NPC1KDM4ECNR1SMN1; SMN2
	SCHEMBL5035139	0.82	CYP3A4 (0.43)	CYP3A4NPC1TP53KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.