Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL518644 | 0.91 | TSHR (0.38) | TSHRLMNAKDM4ECA12CA14 | |
| SCHEMBL28465040 | 0.83 | LMNA (0.39) | TSHRLMNAKDM4EKMT2AALDH1A1 | |
| SCHEMBL28098323 | 0.83 | ALDH1A1 (0.44) | TSHRLMNAKDM4ECA12CA14 | |
| SCHEMBL2449985 | 0.83 | TSHR (0.42) | TSHRLMNAKDM4ECA12CA14 | |
| SCHEMBL10836953 | 0.83 | CNR2 (0.45) | TSHRLMNACA12CA14KMT2A | |
| Ammonia Solution, Strong SCHEMBL27715413 | 0.83 | CNR2 (0.34) | LMNAKDM4ECNR2CNR1 | |
| SCHEMBL10627995 | 0.82 | LMNA (0.38) | TSHRLMNAKDM4EKMT2AALDH1A1 | |
| SCHEMBL28056206 | 0.82 | ALDH1A1 (0.43) | TSHRLMNAKDM4ECA12CA14 | |
| SCHEMBL888076 | 0.82 | LMNA (0.38) | TSHRLMNAKDM4EKMT2AALDH1A1 | |
| SCHEMBL2871619 | 0.82 | LMNA (0.38) | TSHRLMNAKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984726-A2 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | Applera Corporation (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007087534-A2 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | APPLERA CORPORATION (US) | 2007-08-02 | — | — | WO | disclosed |