SCHEMBL5035249

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5035881	0.95	KMT2A (0.39)	LMNAMAPTHCRTR1HCRTR2CNR1
	SCHEMBL5032654	0.93	HTR2C (0.43)	LMNAMAPTCNR1CNR2KMT2A
	SCHEMBL5035011	0.89	CYP3A4 (0.41)	CNR1CNR2KMT2AMEN1NPC1
	SCHEMBL5032576	0.89	CNR1 (0.40)	LMNAMAPTHCRTR1HCRTR2CNR1
	SCHEMBL5032570	0.89	CNR1 (0.40)	LMNAMAPTHCRTR1HCRTR2CNR1
	SCHEMBL5032532	0.88	NPC1 (0.37)	LMNAMAPTHCRTR1HCRTR2KMT2A
	SCHEMBL5032530	0.88	HTR2C (0.43)	MAPTCNR2KMT2AMCOLN3MEN1
	SCHEMBL5035014	0.87	TRPC3 (0.41)	LMNAMAPTHCRTR1HCRTR2NPC1
	SCHEMBL5032537	0.87	CYP3A4 (0.38)	LMNAMAPTKMT2ACRHBPCRHR2
	SCHEMBL5032649	0.86	ALDH1A1 (0.48)	LMNAMAPTNPC1RAB9AGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.