Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MYB | P10242 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5040310 | 0.77 | EDNRA (0.45) | CYP3A4KDM4ECYP1A2CYP2C9CA2 | |
| SCHEMBL8443282 | 0.76 | ICAM1 (0.56) | CYP3A4KDM4ECYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL5034044 | 0.75 | ALDH1A1 (0.41) | HDAC4HDAC8CYP3A4KDM4ECYP1A2 | |
| SCHEMBL15772943 | 0.73 | IDO1 (0.45) | IDO1HDAC4HDAC8CYP3A4KDM4E | |
| SCHEMBL24926176 | 0.72 | SMN1; SMN2 (0.50) | HDAC4HDAC8CYP3A4KDM4ECA2 | |
| SCHEMBL25871284 | 0.72 | CA2 (0.48) | CYP3A4KDM4ECYP1A2CYP2C9CA2 | |
| SCHEMBL19612390 | 0.71 | SLC6A4 (0.39) | IDO1HDAC4HDAC8KDM4ECYP1A2 | |
| SCHEMBL19612192 | 0.69 | SMN1; SMN2 (0.47) | HDAC4HDAC8CYP3A4KDM4ECA2 | |
| SCHEMBL10602566 | 0.68 | MCHR1 (0.46) | HDAC4HDAC8KDM4ECYP1A2CYP2C9 | |
| SCHEMBL13232420 | 0.68 | KDM4E (0.46) | HDAC4HDAC8CYP3A4KDM4ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585745-A4 | FC RECEPTOR MODULATING COMPOUNDS AND COMPOSITIONS | TRILLIUM THERAPEUTICS INC (CA) | 2008-07-09 | — | — | EP | disclosed |
| EP-1585745-A1 | FC RECEPTOR MODULATING COMPOUNDS AND COMPOSITIONS | Arthron Limited (AU) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004058747-A1 | FC RECEPTOR MODULATING COMPOUNDS AND COMPOSITIONS | ARTHRON LIMITED (AU) | 2004-07-15 | — | — | WO | disclosed |