Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | CPA3 | P15088 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323763 | 0.88 | CACNA1B (0.49) | CYP2D6ALDH1A1CYP1A2TSHRCYP2C19 | |
| SCHEMBL7076635 | 0.88 | TBXAS1 (0.45) | CYP2D6ALDH1A1CYP1A2TSHRCYP2C19 | |
| SCHEMBL7324322 | 0.88 | CNR1 (0.58) | CYP2D6ALDH1A1CYP1A2TSHRCYP2C19 | |
| SCHEMBL5692956 | 0.86 | TBXAS1 (0.63) | CYP2D6ALDH1A1CYP1A2TSHRCYP2C19 | |
| SCHEMBL8494351 | 0.86 | MTNR1A (0.52) | CYP2D6TBXAS1MTNR1AMTNR1BEPHX2 | |
| SCHEMBL3154532 | 0.85 | TBXAS1 (0.71) | CYP2D6ALDH1A1CYP1A2TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL2861647 | 0.85 | TBXAS1 (0.61) | CYP2D6ALDH1A1CYP1A2TSHRCYP2C19 | |
| SCHEMBL14360103 | 0.84 | GABBR2 (0.53) | CYP2D6ALDH1A1CYP1A2TSHRCYP2C19 | |
| SCHEMBL9423408 | 0.84 | CNR2 (0.61) | CYP2D6ALDH1A1CYP1A2CYP2C19MTNR1A | |
| SCHEMBL8922507 | 0.84 | CASR (0.52) | ALDH1A1CNR1HPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161962-A | Sulphonic-acid-amide derivative | KONO PHARMACEUTICAL IND K K (JP) | 1997-10-15 | — | — | CN | claimed |
| WO-2024238340-A2 | SMALL MOLECULE VGSC INHIBITORS, PHARMACEUTICAL COMPOSITION COMPRISING SAID SMALL MOLECULES, THERAPEUTIC USE THEREOF | THE UAB RESEARCH FOUNDATION (US) | 2024-11-21 | — | — | WO | disclosed |
| CN-115806531-B | Preparation method of 4, 5-dihydro-5, 5-diphenyl isoxazole-3-formic acid and derivatives thereof | 新发药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115806531-B | Preparation method of 4, 5-dihydro-5, 5-diphenyl isoxazole-3-formic acid and derivatives thereof | 新发药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115819208-B | Synthesis method of 2-aryl-3, 4-dihydro-1 (2H) -naphthalenone compound | 浙大城市学院 | 2023-12-12 | — | — | CN | disclosed |
| CN-115819208-A | Synthetic method of 2-aryl-3, 4-dihydro-1 (2H) -naphthalenone compound | 浙大城市学院 | 2023-03-21 | — | — | CN | disclosed |
| CN-115806531-A | Preparation method of 4, 5-dihydro-5, 5-diphenyl isoxazole-3-formic acid and derivatives thereof | 新发药业有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-115806531-A | Preparation method of 4, 5-dihydro-5, 5-diphenyl isoxazole-3-formic acid and derivatives thereof | 新发药业有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-111182880-A | WNT compositions and processes performed from serum-free culture conditions | 安卡萨再生疗法公司 | 2020-05-19 | — | — | CN | disclosed |
| US-20160075732-A1 | RADICAL ORBITAL SWITCHING | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2016-03-17 | — | — | US | disclosed |
| US-4839104-A | Process for preparing sertraline intermediates | PFIZER, INC. (US) | 1989-06-13 | — | — | US | disclosed |
| CN-1031837-A | Process for the preparation of intermediates of cis- (1S) (4S) -N-methyl-4- (3, 4-dichlorophenyl) -1, 2, 3, 4 tetrachloro-1-naphthylamine | PFIZER (US) | 1989-03-22 | — | — | CN | disclosed |
| EP-0295050-A1 | Process for preparing a 4,4-diphenylbutanoic acid derivative | PFIZER INC. (US) | 1988-12-14 | — | — | EP | disclosed |
| EP-0295050-A1 | Process for preparing a 4,4-diphenylbutanoic acid derivative | PFIZER INC. (US) | 1988-12-14 | — | — | EP | disclosed |
| EP-0294220-A2 | Photopolymerizable composition | Hitachi Chemical Co., Ltd. (JP) | 1988-12-07 | — | — | EP | disclosed |
| US-4777288-A | Process for preparing a 4,4-diphenylbutanoic acid derivative | PFIZER INC. (US) | 1988-10-11 | — | — | US | disclosed |
| US-4777288-A | Process for preparing a 4,4-diphenylbutanoic acid derivative | PFIZER INC. (US) | 1988-10-11 | — | — | US | disclosed |
| EP-0071920-B1 | PROCESS FOR THE CARBONYLATION OF FORMALDEHYDE ACETALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-11 | — | — | EP | disclosed |
| EP-0071920-A2 | Process for the carbonylation of formaldehyde acetals | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-16 | — | — | EP | disclosed |
| US-4148968-A | COLORLESS TONER, A POLYMER OR CLAY AND A FATTY ACID OR DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 1979-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075732-A1 | RADICAL ORBITAL SWITCHING | RAD1, RAD54L, NQO1 | CYP2D6 607/4885ALDH1A1 183/4885CYP1A2 1710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.