⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1567601 | 0.97 | — | — | |
| SCHEMBL455723 | 0.81 | TP53 (0.31) | — | |
| SCHEMBL309238 | 0.75 | — | — | |
| SCHEMBL28463785 | 0.74 | — | — | |
| SCHEMBL3447684 | 0.73 | — | — | |
| SCHEMBL20160771 | 0.72 | DNM1 (0.40) | — | |
| SCHEMBL14314301 | 0.72 | — | — | |
| SCHEMBL23952854 | 0.71 | — | — | |
| SCHEMBL4365811 | 0.71 | — | — | |
| SCHEMBL309203 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375355-B1 | Process for the catalytic reforming of alkylene amines to linearly-extended polyalkylene polyamines | DOW CHEMICAL CO (US) | 1994-02-02 | — | — | EP | claimed |
| US-8293075-B2 | Method for the continuous separation by distillation of mixtures that contain morphonline (MO), monoaminodiglycol (ADG), ammonia and water by means of distillation | BASF SE (DE) | 2012-10-23 | — | — | US | disclosed |
| US-8178525-B2 | FXA inhibitors with cyclic amidoxime or cyclic amidrazone as P4 subunit, processes for their preparations, and pharmaceutical compositions and derivatives thereof | LEGOCHEM BIOSCIENCE LTD. (KR) | 2012-05-15 | — | — | US | disclosed |
| US-8178525-B2 | FXA inhibitors with cyclic amidoxime or cyclic amidrazone as P4 subunit, processes for their preparations, and pharmaceutical compositions and derivatives thereof | LEGOCHEM BIOSCIENCE LTD. (KR) | 2012-05-15 | — | — | US | disclosed |
| US-20120024689-A1 | METHOD FOR THE CONTINUOUS SEPARATION OF MIXTURES COMPRISING MORPHONLINE (MO), MONOAMINODIGLYCOL (ADG), AMMONIA AND WATER BY MEANS OF DISTILLATION | BASF SE (DE) | 2012-02-02 | — | — | US | disclosed |
| US-20110112083-A1 | FXA INHIBITORS WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF | LEGOCHEM BIOSCIENCE LTD. (KR) | 2011-05-12 | — | — | US | disclosed |
| US-20110112083-A1 | FXA INHIBITORS WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF | LEGOCHEM BIOSCIENCE LTD. (KR) | 2011-05-12 | — | — | US | disclosed |
| WO-2010002115-A2 | FXA INHIBITORS WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF | LEGOCHEM BIOSCIENCE LTD. (KR) | 2010-01-07 | — | — | WO | disclosed |
| US-5554793-A | NIOBIUM PHOSPHATE CATALYST | THE DOW CHEMICAL COMPANY (US) | 1996-09-10 | — | — | US | disclosed |
| US-5410087-A | Forming high and low molecular weight polyalkylene-amines and alkyleneamines in presence of group 6 catalyst; cracking | THE DOW CHEMICAL COMPANY (US) | 1995-04-25 | — | — | US | disclosed |
| US-5288909-A | Group 5B catalyst, such as niobic acid | THE DOW CHEMICAL COMPANY (US) | 1994-02-22 | — | — | US | disclosed |
| EP-0375355-B1 | Process for the catalytic reforming of alkylene amines to linearly-extended polyalkylene polyamines | DOW CHEMICAL CO (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5256786-A | Catalytic reforming of cyclic alkyleneamines | THE DOW CHEMICAL COMPANY (US) | 1993-10-26 | — | — | US | disclosed |
| WO-1993018017-A1 | CATALYTIC REFORMING OF CYCLIC ALKYLENEAMINES | THE DOW CHEMICAL COMPANY (US) | 1993-09-16 | — | — | WO | disclosed |
| US-5210307-A | Thorium silicate catalyst | THE DOW CHEMICAL COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| US-5166442-A | Group IIA metal silicates as catalysts | THE DOW CHEMICAL COMPANY (US) | 1992-11-24 | — | — | US | disclosed |
| US-5118850-A | Catalytic reforming of alkyleneamines to linearly-extended polyalkylenepolyamines | THE DOW CHEMICAL COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| US-4996363-A | Contacting with Group 2A metal silicate catalyst; aluminum-free | THE DOW CHEMICAL COMPANY (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0384766-A2 | Process of preparing linearly-extended polyalkylenepolyamines | THE DOW CHEMICAL COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |
| EP-0375355-A2 | Process for the catalytic reforming of alkylene amines to linearly-extended polyalkylene polyamines | THE DOW CHEMICAL COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |