SCHEMBL5035750

SCHEMBL5035750

CCC(Nc1nc(Cl)nc(Nc2ccc(OC)c(F)c2)n1)C1CCCN1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GALR1 P47211 4/20 0.42
APP P05067 2/20 0.41
GALR2 O43603 4/20 0.39
SOS1 Q07889 1/20 0.39
MAPK1 P28482 1/20 0.37
BCL6 P41182 3/20 0.37
MAPT P10636 3/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
KMT2A Q03164 1/20 0.37
CDK1 P06493 1/20 0.36
CDK4 P11802 1/20 0.36
CCNB1 P14635 1/20 0.36
CCND1 P24385 1/20 0.36
CCNE1 P24864 1/20 0.36
CDK2 P24941 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 2/20 0.35
EHMT2 Q96KQ7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4832502 0.95 GALR1 (0.45) GALR1GALR2SOS1MAPK1BCL6
SCHEMBL5434500 0.91 GALR1 (0.42) GALR1GALR2SOS1MAPK1MEN1
SCHEMBL6207968 0.91 GALR1 (0.42) GALR1GALR2SOS1MAPK1CDK1
SCHEMBL4832251 0.90 GALR1 (0.42) GALR1GALR2MAPK1BCL6CDK1
SCHEMBL5553430 0.90 GALR1 (0.41) GALR1GALR2SOS1MAPK1CDK1
SCHEMBL5031363 0.89 GALR1 (0.50) GALR1GALR2SOS1MAPK1CDK1
SCHEMBL6013841 0.89 GALR1 (0.44) GALR1GALR2MAPK1BCL6MAPT
SCHEMBL4832646 0.89 GALR1 (0.44) GALR1GALR2MAPK1BCL6MAPT
SCHEMBL5553410 0.89 GALR1 (0.41) GALR1GALR2SOS1MAPK1CDK1
SCHEMBL4829617 0.89 GALR1 (0.44) GALR1GALR2MAPK1BCL6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7335770-B2 Triazine compounds and their analogs, compositions, and methods REDDY U5 THERAPEUTICS, INC. (US) 2008-02-26 US disclosed
US-20050227983-A1 Triazine compounds and their analogs, compositions, and methods DR. REDDY'S LABORATORIES LTD. (IN) 2005-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050227983-A1 Triazine compounds and their analogs, compositions, and methods MYLK, SMAD3, GID4 GALR1 1307/4885APP 2043/4885GALR2 1003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.