⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705752 | 0.75 | — | — | |
| SCHEMBL2706452 | 0.75 | — | — | |
| SCHEMBL7804757 | 0.75 | — | — | |
| SCHEMBL25948776 | 0.75 | — | — | |
| SCHEMBL28056778 | 0.75 | — | — | |
| SCHEMBL25873238 | 0.75 | — | — | |
| SCHEMBL27995425 | 0.73 | APLNR (0.34) | — | |
| SCHEMBL27995429 | 0.71 | APLNR (0.38) | — | |
| SCHEMBL4203277 | 0.71 | PRCP (0.32) | — | |
| SCHEMBL2706479 | 0.70 | APLNR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412964-A | Substituted heterocyclic compounds and their use | 首药控股(北京)股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| EP-1263730-B1 | AMINE DERIVATIVES FOR THE TREATMENT OF APOPTOSIS | SERONO LAB (CH) | 2008-01-09 | — | — | EP | disclosed |
| CN-1188410-C | Nonsteroid IL-5 inhibitor, its preparation method and medical composition containing the inhibitor | JANSSEN PHARMACEUTICA NV (BE) | 2005-02-09 | — | — | CN | disclosed |
| US-6770656-B2 | NEURODEGENERATIVE DISORDERS; ANTIEPILEPTIC AND ANTIISCHEMIC AGENTS; INFERTILITY, CARDIOVASCULAR DISORDERS, RENAL HYPOXIA, HEPATITIS AND AIDS TREATMENT | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2004-08-03 | — | — | US | disclosed |
| US-20030216427-A1 | Amine derivatives for the treatment of apoptosis | MERCK SERONO SA (CH) | 2003-11-20 | — | — | US | disclosed |
| CN-1368972-A | Non-steroidal IL-5 inhibitors, process for their preparation and pharmaceutical compositions containing them | JANSSEN PHARMACEUTICA NV (BE) | 2002-09-11 | — | — | CN | disclosed |