Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952399 | 0.86 | TSHR (0.33) | ALDH1A1TSHR | |
| SCHEMBL277292 | 0.83 | CYP2C19 (0.32) | ALDH1A1CYP2C19TSHRMEN1GLA | |
| SCHEMBL24831752 | 0.82 | TSHR (0.48) | ALDH1A1CYP2C19TSHRMEN1GLA | |
| SCHEMBL26564065 | 0.82 | TSHR (0.48) | ALDH1A1CYP2C19TSHRMEN1GLA | |
| SCHEMBL6283490 | 0.82 | TSHR (0.48) | ALDH1A1CYP2C19TSHRMEN1GLA | |
| SCHEMBL31008679 | 0.81 | ALDH1A1 (0.30) | ALDH1A1CYP2C19TSHRMEN1GLA | |
| SCHEMBL22644464 | 0.80 | TSHR (0.59) | ALDH1A1CYP2C19TSHRMEN1GLA | |
| SCHEMBL24003117 | 0.80 | TSHR (0.59) | ALDH1A1CYP2C19TSHRMEN1GLA | |
| SCHEMBL13661597 | 0.80 | TSHR (0.32) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL19407254 | 0.80 | TSHR (0.32) | ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233770-B1 | PHOSPHONATE COMPOUNDS | UNIV CALIFORNIA AT SAN DIEGO (US) | 2008-02-13 | — | — | EP | claimed |
| EP-3330256-B1 | HETEROCYCLIC DERIVATIVE HAVING TrkA-INHIBITING ACTIVITY | SHIONOGI & CO (JP) | 2021-06-16 | — | — | EP | disclosed |