Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 2/20 | 0.36 |
| ▸ | ADH1C | P00326 | 2/20 | 0.36 |
| ▸ | ADH1A | P07327 | 2/20 | 0.36 |
| ▸ | ADH7 | P40394 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26564065 | 1.00 | TSHR (0.48) | TSHRALDH1A1CYP3A4CYP2C19MEN1 | |
| SCHEMBL24831752 | 1.00 | TSHR (0.48) | TSHRALDH1A1CYP3A4CYP2C19MEN1 | |
| SCHEMBL22644464 | 0.93 | TSHR (0.59) | TSHRALDH1A1CYP3A4CYP2C19MEN1 | |
| SCHEMBL24003117 | 0.93 | TSHR (0.59) | TSHRALDH1A1CYP3A4CYP2C19MEN1 | |
| SCHEMBL6280015 | 0.91 | TSHR (0.56) | TSHRALDH1A1CYP3A4CYP2C19ADH1B | |
| SCHEMBL14469367 | 0.91 | TSHR (0.56) | TSHRALDH1A1CYP3A4CYP2C19ADH1B | |
| SCHEMBL6285476 | 0.91 | TSHR (0.56) | TSHRALDH1A1CYP3A4CYP2C19ADH1B | |
| SCHEMBL6285010 | 0.91 | TSHR (0.56) | TSHRALDH1A1CYP3A4CYP2C19ADH1B | |
| SCHEMBL20906860 | 0.91 | TSHR (0.48) | TSHRALDH1A1CYP3A4CYP2C19MEN1 | |
| SCHEMBL22421817 | 0.88 | TSHR (0.52) | TSHRALDH1A1CYP3A4CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |
| WO-2022040002-A1 | METHODS AND COMPOSITIONS FOR TARGETING PD-L1 | ALIGOS THERAPEUTICS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |
| CN-1284626-C | Fluorinated zwitterionic cocatalyst activators for olefin polymerization | EXXONMOBIL CHEM PATENTS INC (US) | 2006-11-15 | — | — | CN | disclosed |
| US-6919291-B2 | Fluorinated zwitterionic cocatalyst activators for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20040110631-A1 | Fluorinated zwitterionic cocatalyst activators for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-06-10 | — | — | US | disclosed |
| CN-1477995-A | Fluorinated zwitterionic cocatalyst activators for olefin polymerization | 埃克森美孚化学专利公司 | 2004-02-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110631-A1 | Fluorinated zwitterionic cocatalyst activators for olefin polymerization | FZD7, FOS, COG4 | TSHR 4247/4885ALDH1A1 3691/4885CYP3A4 1344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.