SCHEMBL503607

SCHEMBL503607

Cc1c(F)c(F)c(C(=O)O)c(F)c1F

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 14/20 0.47
TAS1R1 Q7RTX1 13/20 0.47
TAS1R2 Q8TE23 13/20 0.47
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPK1 P28482 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27805263 0.97 TAS1R3 (0.45) TAS1R3TAS1R1TAS1R2MEN1KMT2A
Hydrochloric Acid SCHEMBL6740806 0.97 TAS1R3 (0.45) TAS1R3TAS1R1TAS1R2MEN1KMT2A
SCHEMBL2860749 0.95 TAS1R3 (0.44) TAS1R3TAS1R1TAS1R2MEN1KMT2A
SCHEMBL7074989 0.92 TAS1R3 (0.41) TAS1R3TAS1R1TAS1R2MEN1KMT2A
SCHEMBL13447235 0.92 TAS1R3 (0.41) TAS1R3TAS1R1TAS1R2MEN1KMT2A
SCHEMBL2470702 0.92 TAS1R3 (0.45) TAS1R3TAS1R1TAS1R2MEN1KMT2A
SCHEMBL545012 0.89 HCAR2 (0.41) TAS1R3TAS1R1TAS1R2MEN1KMT2A
SCHEMBL2921028 0.89 TAS1R3 (0.38) TAS1R3TAS1R1TAS1R2MEN1KMT2A
SCHEMBL19130691 0.89 MEN1 (0.41) TAS1R3TAS1R1TAS1R2MEN1KMT2A
SCHEMBL2011531 0.89 MEN1 (0.46) TAS1R3TAS1R1TAS1R2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-111892667-B Application of fluorine-containing compound modified cationic polymer in preparation of medical cosmetic and health care products 苏州大学 2024-02-20 CN claimed
CN-111848832-B Application of fluorine-containing compound modified cationic polymer as drug carrier and preparation method thereof 苏州大学 2024-02-20 CN claimed
CN-111848831-B Application of fluorine-containing compound modified cationic polymer in preparation of vaccine medicine 苏州大学 2023-06-13 CN claimed
EP-4095162-A1 APPLICATION OF AND PREPARATION METHOD FOR CATIONIC POLYMER MODIFIED BY FLUORINE-CONTAINING COMPOUND AS DRUG CARRIER Soochow University (CN) 2022-11-30 EP claimed
US-20220273806-A1 USE OF FLUORINE-CONTAINING COMPOUND-MODIFIED CATIONIC POLYMER AS DRUG CARRIER AND PREPARATION METHOD SOOCHOW UNIVERSITY (CN) 2022-09-01 US claimed
WO-2021147585-A1 USE OF CHITOSAN MODIFIED BY FLUORINE-CONTAINING COMPOUND AS DRUG CARRIER AND PREPARATION METHOD THEREFOR 苏州大学 2021-07-29 WO claimed
WO-2021147598-A1 APPLICATION OF AND PREPARATION METHOD FOR CATIONIC POLYMER MODIFIED BY FLUORINE-CONTAINING COMPOUND AS DRUG CARRIER 苏州大学 2021-07-29 WO claimed
CN-111892667-A Application of cationic polymer modified by fluorine-containing compound in preparation of medical beauty and health care products 苏州大学 2020-11-06 CN claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273806-A1 USE OF FLUORINE-CONTAINING COMPOUND-MODIFIED CATIONIC POLYMER AS DRUG CARRIER AND PREPARATION METHOD F12, SLCO4C1, SLC7A1 TAS1R3 571/4885TAS1R1 218/4885TAS1R2 423/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 TAS1R3 1889/4885TAS1R1 2623/4885TAS1R2 2330/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 TAS1R3 1031/4885TAS1R1 1032/4885TAS1R2 1178/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS TAS1R3 4440/4885TAS1R1 4355/4885TAS1R2 4495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.