Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 7/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2768030 | 0.84 | ACACB (0.46) | ACACBACACA | |
| SCHEMBL12341891 | 0.84 | ACACB (0.46) | ACACBACACA | |
| SCHEMBL25236788 | 0.80 | ACACB (0.60) | ACACB | |
| SCHEMBL3708275 | 0.80 | ACACB (0.60) | ACACB | |
| SCHEMBL13075567 | 0.78 | LRRK2 (0.44) | GPR139NAMPTLIPGCNR1CNR2 | |
| SCHEMBL319805 | 0.78 | LRRK2 (0.44) | GPR139NAMPTLIPGCNR1CNR2 | |
| SCHEMBL13759318 | 0.77 | GPR139 (0.49) | GPR139ACACBACACA | |
| SCHEMBL13759315 | 0.77 | GPR139 (0.49) | GPR139ACACBACACA | |
| SCHEMBL7723724 | 0.77 | GPR139 (0.49) | GPR139ACACBACACA | |
| SCHEMBL13452335 | 0.77 | ALDH1A1 (0.49) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1889903-A1 | Biocatalysts with amine acylase activity | Novartis AG (CH) | 2008-02-20 | — | — | EP | disclosed |
| EP-0954571-B1 | BIOCATALYSTS WITH AMINE ACYLASE ACTIVITY | NOVARTIS AG (CH) | 2007-08-29 | — | — | EP | disclosed |
| US-6235516-B1 | FROM RHODOCOCCUS GLOBERULUS, RHODOCOCCUS EQUI OR ARTHROBACTER AURESCENS | NOVARTIS AG (CH) | 2001-05-22 | — | — | US | disclosed |
| EP-0954571-A1 | BIOCATALYSTS WITH AMINE ACYLASE ACTIVITY | Novartis AG (CH) | 1999-11-10 | — | — | EP | disclosed |
| WO-1997041214-A1 | BIOCATALYSTS WITH AMINE ACYLASE ACTIVITY | NOVARTIS AG (CH) | 1997-11-06 | — | — | WO | disclosed |