Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | F13A1 | P00488 | 1/20 | 0.49 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.48 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007111 | 0.86 | CNR1 (0.62) | CNR1RAB9ALMNAALDH1A1HPGD | |
| SCHEMBL19002541 | 0.85 | MTNR1A (0.62) | CNR1RAB9ALMNAHPGDGAA | |
| SCHEMBL19049570 | 0.85 | CNR1 (0.61) | CNR1RAB9ALMNAHPGDGAA | |
| SCHEMBL38654611 | 0.84 | ERCC1 (0.59) | CNR1LMNAMEP1AMEP1BERCC1 | |
| SCHEMBL8645386 | 0.84 | ERCC1 (0.59) | CNR1LMNAMEP1AMEP1BERCC1 | |
| SCHEMBL19002632 | 0.84 | CNR1 (0.57) | CNR1RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL10591303 | 0.84 | KDM4E (0.66) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL12720885 | 0.82 | SPR (0.67) | CNR1RAB9AMAPTHPGDGAA | |
| SCHEMBL19002549 | 0.82 | CNR1 (0.55) | CNR1RAB9AKDM4ELMNAALDH1A1 | |
| SCHEMBL27718551 | 0.81 | CNR1 (0.54) | CNR1RAB9AKDM4EGAAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3394056-B1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC (US) | 2021-04-14 | — | — | EP | disclosed |
| CN-107922428-A | Thienopyrroles compound and its purposes as the inhibitor for piercing shrimp source property luciferase | 普洛麦格公司 | 2018-04-17 | — | — | CN | disclosed |
| EP-1889903-A1 | Biocatalysts with amine acylase activity | Novartis AG (CH) | 2008-02-20 | — | — | EP | disclosed |
| EP-0954571-B1 | BIOCATALYSTS WITH AMINE ACYLASE ACTIVITY | NOVARTIS AG (CH) | 2007-08-29 | — | — | EP | disclosed |
| US-6235516-B1 | FROM RHODOCOCCUS GLOBERULUS, RHODOCOCCUS EQUI OR ARTHROBACTER AURESCENS | NOVARTIS AG (CH) | 2001-05-22 | — | — | US | disclosed |
| EP-0954571-A1 | BIOCATALYSTS WITH AMINE ACYLASE ACTIVITY | Novartis AG (CH) | 1999-11-10 | — | — | EP | disclosed |
| WO-1997041214-A1 | BIOCATALYSTS WITH AMINE ACYLASE ACTIVITY | NOVARTIS AG (CH) | 1997-11-06 | — | — | WO | disclosed |