⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29838746 | 0.79 | LMNA (0.36) | — | |
| SCHEMBL2104477 | 0.75 | — | — | |
| SCHEMBL310077 | 0.73 | — | — | |
| SCHEMBL12929093 | 0.73 | — | — | |
| SCHEMBL3292391 | 0.73 | — | — | |
| SCHEMBL9822324 | 0.72 | — | — | |
| SCHEMBL510219 | 0.71 | — | — | |
| SCHEMBL6512721 | 0.71 | — | — | |
| SCHEMBL8083388 | 0.71 | — | — | |
| SCHEMBL8997863 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432417-B1 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER | AVENTIS PHARMA SA (FR) | 2008-02-20 | — | — | EP | disclosed |
| CN-1312535-C | Optical photoresist stripping composition and cleaning composition | MITSUBISHI GAS CHEMICAL CO (JP) | 2007-04-25 | — | — | CN | disclosed |
| US-7041668-B2 | Substituted benzimidazole compounds and their use for the treatment of cancer | AVENTIS PHARMA S.A. (FR) | 2006-05-09 | — | — | US | disclosed |
| US-20050014811-A1 | Substituted benzimidazole compounds and their use for the treatment of cancer | AVENTIS PHARMA S.A. (FR) | 2005-01-20 | — | — | US | disclosed |
| CN-1444103-A | Optical photoresist stripping composition and cleaning composition | MITSUBISHI GAS CHEMICAL CO (JP) | 2003-09-24 | — | — | CN | disclosed |
| EP-1298125-A1 | Substituted benzimidazole compounds and their use for the treatment of cancer | Aventis Pharma S.A. (FR) | 2003-04-02 | — | — | EP | disclosed |