⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12929093 | 0.73 | — | — | |
| SCHEMBL5036375 | 0.71 | — | — | |
| SCHEMBL22283562 | 0.69 | — | — | |
| SCHEMBL9822324 | 0.67 | — | — | |
| SCHEMBL20639303 | 0.67 | GABRP (0.32) | — | |
| SCHEMBL29200235 | 0.67 | GABRP (0.32) | — | |
| SCHEMBL14296554 | 0.65 | — | — | |
| SCHEMBL7212086 | 0.65 | — | — | |
| SCHEMBL6403677 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL4254986 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523303-A | ANTIULCER AND -SECRETORY AGENTS; GASTRIC H+K+ ATPASE INHIBITORS; NONTOXIC; OXIMES DERIVATIVES | EGIS GYOGYSZERGYAR RT. (HU) | 1996-06-04 | — | — | US | disclosed |
| EP-0619298-A2 | (Phenylmethylene)-2-(alkyl)-1- omega-(amino)-alkoxyimino -cycloalkane derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |
| US-5234934-A | Derivatives of a 1-(2-hydroxy-3-N-hetpropoxyimino)-2-phenyl methylene)cycloalkane; antiarrhymia,-secretory and -inflammatory agents; tranquilizers; local anaesthetics | EGIS GYOGYSZERGYAR (HU) | 1993-08-10 | — | — | US | disclosed |
| US-5130487-A | Cardiovascular disorders, tranquilizers for central nervous systems or for digestive system problems | EGIS GYOGYSZERGYAR (HU) | 1992-07-14 | — | — | US | disclosed |