Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979885 | 0.85 | PTK2B (0.36) | HSD17B10PTK2BL3MBTL1HTR2AALDH1A1 | |
| SCHEMBL19417627 | 0.84 | GABRA1 (0.41) | GABRA1GABRB2HSD17B10PTK2BL3MBTL1 | |
| SCHEMBL1041519 | 0.82 | HSD17B10 (0.41) | HSD17B10PTK2BL3MBTL1PARP1ALDH1A1 | |
| SCHEMBL30226846 | 0.82 | HSD17B10 (0.41) | HSD17B10PTK2BL3MBTL1PARP1ALDH1A1 | |
| SCHEMBL2518088 | 0.81 | PPARG (0.36) | HSD17B10PTK2BL3MBTL1HTR2AALDH1A1 | |
| SCHEMBL29396009 | 0.78 | GABRA1 (0.44) | GABRA1GABRB2CLCN2ALDH1A1HPGD | |
| SCHEMBL721894 | 0.78 | GABRA1 (0.44) | GABRA1GABRB2CLCN2ALDH1A1HPGD | |
| SCHEMBL3244580 | 0.77 | GABRA1 (0.52) | GABRA1GABRB2HSD17B10ELANEDAO | |
| SCHEMBL13837650 | 0.77 | HSD17B10 (0.42) | HSD17B10PTK2BL3MBTL1ALDH1A1HPGD | |
| SCHEMBL1362480 | 0.77 | GABRA1 (0.45) | GABRA1GABRB2CLCN2PARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402645-B2 | Soluble polyfunctional vinyl aromatic polymer and method of producing the same | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2008-07-22 | — | — | US | disclosed |
| US-20070155923-A1 | Soluble polyfunctional vinyl aromatic polymer and method of producing the same | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2007-07-05 | — | — | US | disclosed |