Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798296 | 0.91 | KCNH2 (0.42) | KCNH2HTR1ASLC6A4CNR1CNR2 | |
| SCHEMBL5039995 | 0.91 | KCNH2 (0.48) | KCNH2HTR1ASLC6A4OPRM1CNR1 | |
| SCHEMBL5036618 | 0.90 | KCNH2 (0.47) | KCNH2HTR1ASLC6A4OPRM1CNR1 | |
| SCHEMBL5042261 | 0.90 | KCNH2 (0.48) | KCNH2HTR1ASLC6A4OPRM1CNR1 | |
| SCHEMBL5040333 | 0.89 | KCNH2 (0.58) | KCNH2HTR1ASLC6A4OPRM1CNR2 | |
| SCHEMBL2798542 | 0.89 | KCNH2 (0.49) | KCNH2HTR1ASLC6A4OPRM1CNR2 | |
| SCHEMBL5040949 | 0.88 | KCNH2 (0.49) | KCNH2HTR1ASLC6A4CNR1CNR2 | |
| SCHEMBL5044554 | 0.88 | KCNH2 (0.47) | KCNH2HTR1ASLC6A4OPRM1CNR1 | |
| SCHEMBL5040315 | 0.87 | KCNH2 (0.46) | KCNH2HTR1ASLC6A4OPRM1CNR1 | |
| SCHEMBL2798220 | 0.87 | KCNH2 (0.46) | KCNH2HTR1ASLC6A4OPRM1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |
| EP-1900732-A1 | NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-03-19 | — | — | EP | disclosed |