Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.55 |
| ▸ | TUBB | P07437 | 4/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352960 | 1.00 | NPSR1 (0.76) | NPSR1TSHRBLMTUBB1TUBB4A | |
| SCHEMBL10085812 | 1.00 | NPSR1 (0.76) | NPSR1TSHRBLMTUBB1TUBB4A | |
| SCHEMBL9065486 | 0.94 | TSHR (0.88) | NPSR1TSHRBLMTUBB1TUBB4A | |
| SCHEMBL134326 | 0.86 | TSHR (1.00) | NPSR1TSHRBLMGAAACHE | |
| SCHEMBL1243722 | 0.86 | TSHR (1.00) | NPSR1TSHRBLMGAAACHE | |
| SCHEMBL10085823 | 0.86 | TSHR (1.00) | NPSR1TSHRBLMGAAACHE | |
| SCHEMBL140947 | 0.86 | TSHR (1.00) | NPSR1TSHRBLMGAAACHE | |
| SCHEMBL187137 | 0.86 | NPSR1 (0.75) | NPSR1TSHRBLMACHEALDH1A1 | |
| SCHEMBL187138 | 0.86 | NPSR1 (0.75) | NPSR1TSHRBLMACHEALDH1A1 | |
| SCHEMBL20566321 | 0.85 | BLM (0.91) | NPSR1TSHRBLMGAAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8287764-B2 | Coated particles | AKZO NOBEL N.V. (NL) | 2012-10-16 | — | — | US | claimed |
| US-8114775-B2 | Dihydroxy enol compounds used in chemical mechanical polishing compositions having metal ion oxidizers | DUPONT AIR PRODUCTS NANOMATERIALS, LLC (US) | 2012-02-14 | — | — | US | claimed |
| US-20110133128-A1 | COATED PARTICLES | AKZO NOBEL N.V. (NL) | 2011-06-09 | — | — | US | claimed |
| EP-1871855-B1 | DIHYDROXY ENOL COMPOUNDS USED IN CHEMICAL MECHANICAL POLISHING COMPOSITIONS HAVING METAL ION OXIDIZERS | DUPONT AIR PROD NANOMATERIALS (US) | 2010-03-24 | — | — | EP | claimed |
| US-20090308836-A1 | DIHYDROXY ENOL COMPOUNDS USED IN CHEMICAL MECHANICAL POLISHING COMPOSITIONS HAVING METAL ION OXIDIZERS | VERSUM MATERIALS US, LLC | 2009-12-17 | — | — | US | claimed |
| EP-1023888-B1 | Hair cosmetic composition | KAO CORP (JP) | 2009-03-25 | — | — | EP | claimed |
| EP-1871855-A1 | DIHYDROXY ENOL COMPOUNDS USED IN CHEMICAL MECHANICAL POLISHING COMPOSITIONS HAVING METAL ION OXIDIZERS | DuPont Air Products NanoMaterials L.L.C. (US) | 2008-01-02 | — | — | EP | claimed |
| US-20060270235-A1 | Dihydroxy enol compounds used in chemical mechanical polishing compositions having metal ion oxidizers | VERSUM MATERIALS US, LLC | 2006-11-30 | — | — | US | claimed |
| US-20060269495-A1 | Alpha hydroxy acid compositions | STIEFEL LABORATORIES, INC. | 2006-11-30 | — | — | US | claimed |
| US-20060229258-A1 | Steroidal compositions containing hydroxycarboxylic acids and methods of using the same | STIEFEL LABORATORIES, INC. | 2006-10-12 | — | — | US | claimed |
| EP-0770399-A2 | Additives enhancing topical actions of therapeutic agents | Van Scott, Eugene J., Dr. (US) | 1997-05-02 | — | — | EP | claimed |
| US-5621006-A | TOPICALLY APPLYING IN A VEHICLE, E.G. HYDROXYACIDS, KETOACIDS AND SALTS, ESTERS THEREOF | YU RUEY J (US) | 1997-04-15 | — | — | US | claimed |
| EP-0599819-B1 | Use of hydroxycarboxylic acids and derivatives for the preparation of topical dermatologic compositions for the treatment of wrinkles | SCOTT EUGENE J VAN (US) | 1997-04-02 | — | — | EP | claimed |
| US-5561158-A | Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging | TRISTRATA, INCORPORATED | 1996-10-01 | — | — | US | claimed |
| US-5561157-A | INCLUDES ORGANIC ALPHA AND BETA HYDROXY OR KETO CARBOXYLIC ACIDS, ESTERS, LACTONES AND/OR SALTS; USED FOR SKIN DISORDERS | TRISTRATA INC (US) | 1996-10-01 | — | — | US | claimed |
| US-5554597-A | Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging | TRISTRATA INC (US) | 1996-09-10 | — | — | US | claimed |
| US-5554654-A | COMPRISING SALICYLIC ACID, RETINOIC ACID, ERYTHROMYCIN, METRONIDAZOLE, TETRACYCLINE, CLINDAMYCIN, MINOCYCLINE, MECLOCYCLINE OR BENZILIC ACID BY COMBINING WITH 2-HYDROXY ACID, 2-KETOACID, DERIVATIVE THEREOF OR RELATED COMPOUND | TRISTRATA INC (US) | 1996-09-10 | — | — | US | claimed |
| EP-0273202-B1 | Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. | SCOTT EUGENE J VAN (US) | 1995-06-21 | — | — | EP | claimed |
| EP-0599819-A2 | Additives enhancing topical actions of therapeutic agents | Van Scott, Eugene J., Dr. (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0273202-A2 | Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. | Van Scott, Eugene J., Dr. (US) | 1988-07-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110133128-A1 | COATED PARTICLES | CD63, CD44, S100A4 | NPSR1 3276/4885TSHR 4837/4885BLM 2513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.