Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | BLM | P54132 | 1/20 | 0.75 |
| ▸ | ACHE | P22303 | 2/20 | 0.66 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | TPMT | P51580 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187138 | 1.00 | NPSR1 (0.75) | NPSR1TSHRBLMACHELDHA | |
| SCHEMBL11257010 | 0.87 | TSHR (0.63) | NPSR1TSHRBLMACHEKMT2A | |
| SCHEMBL11256995 | 0.87 | TSHR (0.63) | NPSR1TSHRBLMACHEKMT2A | |
| SCHEMBL352960 | 0.86 | NPSR1 (0.76) | NPSR1TSHRBLMACHEL3MBTL1 | |
| SCHEMBL503700 | 0.86 | NPSR1 (0.76) | NPSR1TSHRBLMACHEL3MBTL1 | |
| SCHEMBL28601945 | 0.86 | TSHR (0.66) | NPSR1TSHRBLMACHELDHA | |
| SCHEMBL10085812 | 0.86 | NPSR1 (0.76) | NPSR1TSHRBLMACHEL3MBTL1 | |
| SCHEMBL28233452 | 0.86 | TSHR (0.66) | NPSR1TSHRBLMACHELDHA | |
| SCHEMBL10085823 | 0.86 | TSHR (1.00) | NPSR1TSHRBLMACHEKMT2A | |
| SCHEMBL140947 | 0.86 | TSHR (1.00) | NPSR1TSHRBLMACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466720-A | Preparation method of veratraldehyde | 重庆欣欣向荣精细化工股份有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-110483264-A | A kind of synthetic method of veratraldehyde | SHANDONG NHU PHARMACEUTICAL CO LTD | 2019-11-22 | — | — | CN | claimed |
| CN-109020813-A | A kind of new method preparing alpha-brominated -3,4- dimethoxyphenylacetic acid ethapon ester | 北京大学 | 2018-12-18 | — | — | CN | claimed |
| CN-117466720-A | Preparation method of veratraldehyde | 重庆欣欣向荣精细化工股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117466720-A | Preparation method of veratraldehyde | 重庆欣欣向荣精细化工股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-113121485-B | 3-aryl coumarin derivative and preparation method and application thereof | 中山大学 | 2023-01-03 | — | — | CN | disclosed |
| CN-113214057-A | Method for synthesizing aromatic aldehyde by Lewis acid catalysis | 西安工程大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-113121485-A | 3-aryl coumarin derivative and preparation method and application thereof | 中山大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-111920797-A | Application of 3-aryl benzofuranone compound | 山东省医学科学院药物研究所（山东省抗衰老研究中心、山东省新技术制药研究所） | 2020-11-13 | — | — | CN | disclosed |
| CN-110483264-A | A kind of synthetic method of veratraldehyde | SHANDONG NHU PHARMACEUTICAL CO LTD | 2019-11-22 | — | — | CN | disclosed |
| CN-110483264-A | A kind of synthetic method of veratraldehyde | SHANDONG NHU PHARMACEUTICAL CO LTD | 2019-11-22 | — | — | CN | disclosed |
| US-20060166997-A1 | Phenylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY | 2006-07-27 | — | — | US | disclosed |
| WO-2006076246-A2 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |
| WO-2006076246-A2 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |
| US-4493823-A | USING CARBOXYBENZENE COMPOUND | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1985-01-15 | — | — | US | disclosed |
| EP-0054174-A2 | Topical cosmetic formulations for the treatment of very greasy hair and seborrhoeic skin | Henkel Kommanditgesellschaft auf Aktien (DE) | 1982-06-23 | — | — | EP | disclosed |
| EP-0005779-B1 | PROCESS FOR THE PREPARATION OF ARYLGLYOXYLIC ACIDS | BAYER AG (DE) | 1980-11-26 | — | — | EP | disclosed |
| US-4218380-A | OXIDATION OF THE A-HYDROXY-ARYLACETIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-19 | — | — | US | disclosed |
| EP-0005779-A2 | Process for the preparation of arylglyoxylic acids | BAYER AG (DE) | 1979-12-12 | — | — | EP | disclosed |
| US-4091214-A | ALPHA-HYDROXY CARBOXYLIC ACID | ELI LILLY AND COMPANY (US) | 1978-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166997-A1 | Phenylglycinamide derivatives useful as anticoagulants | TFPI, SERPINC1, SERPINE1 | NPSR1 3065/4885TSHR 4030/4885BLM 3889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.