Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 15/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24573681 | 0.95 | MEN1 (0.49) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL24573590 | 0.95 | MEN1 (0.49) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL24573685 | 0.86 | MEN1 (0.44) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL24587456 | 0.84 | MEN1 (0.50) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL24587004 | 0.83 | MEN1 (0.49) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL24587564 | 0.83 | MEN1 (0.49) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL14632358 | 0.81 | MEN1 (0.50) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL24573262 | 0.79 | EPHX2 (0.49) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL30563641 | 0.79 | EPHX2 (0.49) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL24587858 | 0.79 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339669-B1 | N-ALKYLATED GABA COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB PHARMA SA (BE) | 2008-06-04 | — | — | EP | disclosed |