SCHEMBL24573262

SCHEMBL24573262

O=C(CCCCCCCNCCO)OCCC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 18/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30563641 1.00 EPHX2 (0.49) EPHX2MEN1KMT2AALDH1A1MAPT
SCHEMBL29672603 0.86 MEN1 (0.48) EPHX2MEN1KMT2AALDH1A1MAPT
SCHEMBL5037099 0.79 MEN1 (0.53) EPHX2MEN1KMT2AALDH1A1MAPT
SCHEMBL9080547 0.73 P2RX7 (0.44) EPHX2MEN1KMT2AALDH1A1MAPT
SCHEMBL6897880 0.72 EPHX2 (0.50) EPHX2MEN1KMT2AALDH1A1MAPT
SCHEMBL18970748 0.72 TP53 (0.45) EPHX2ALDH1A1
SCHEMBL30747769 0.71 MEN1 (0.58) EPHX2MEN1KMT2AALDH1A1MAPT
SCHEMBL31399579 0.71 DGKA (0.61) EPHX2MEN1KMT2A
SCHEMBL31399531 0.71 DGKA (0.61) EPHX2MEN1KMT2A
SCHEMBL19032585 0.71 DGKA (0.61) EPHX2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331656-A1 NANOMATERIALS COMPRISING ACETALS BEAM THERAPEUTICS INC. 2023-10-19 US disclosed
US-20230331657-A1 NANOMATERIALS COMPRISING ESTER-LINKED ACETALS BEAM THERAPEUTICS INC. 2023-10-19 US disclosed
US-20230331657-A1 NANOMATERIALS COMPRISING ESTER-LINKED ACETALS BEAM THERAPEUTICS INC. 2023-10-19 US disclosed
US-20230331656-A1 NANOMATERIALS COMPRISING ACETALS BEAM THERAPEUTICS INC. 2023-10-19 US disclosed
WO-2022140238-A1 NANOMATERIALS COMPRISING ACETALS BEAM THERAPEUTICS INC. (US) 2022-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331657-A1 NANOMATERIALS COMPRISING ESTER-LINKED ACETALS LIPA, SGMS1, SGMS2 EPHX2 318/4885MEN1 1394/4885KMT2A 1791/4885
US-20230331656-A1 NANOMATERIALS COMPRISING ACETALS SGMS1, SGMS2, LIPA EPHX2 1137/4885MEN1 1590/4885KMT2A 1914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.